WDR61 Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI3C8]

CAT#: TA807591AM

WDR61 mouse monoclonal antibody, clone OTI3C8 (formerly 3C8), Biotinylated

Product Images

Immunohistochemical staining of paraffin-embedded Human prostate tissue within the normal limits using anti-WDR61 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer (pH8.5) at 120°C for 3min, TA807591) (1:150)

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  Immunohistochemical staining of paraffin-embedded Carcinoma of Human prostate tissue using anti-WDR61 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer (pH8.5) at 120°C for 3min, TA807591) (1:150)

Specifications

Product Data

• Clone Name: OTI3C8
• Applications: IHC
• Recommended Dilution: IHC 1:150
• Reactivities: Human, Mouse, Rat
• Host: Mouse
• Isotype: IgG2b
• Clonality: Monoclonal
• Immunogen: Human recombinant protein fragment corresponding to amino acids 92-305 of human WDR61(NP_079510) produced in E.coli.
• Formulation: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
• Concentration: 0.5 mg/ml
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Biotin
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 33.4 kDa
• Gene Name: WD repeat domain 61
• Database Link:
  NP_079510
  Entrez Gene 66317 MouseEntrez Gene 363064 RatEntrez Gene 80349 Human
  UniProt ID Q9GZS3
• Background: WDR61 is a subunit of the human PAF and SKI complexes, which function in transcriptional regulation and are involved in events downstream of RNA synthesis, such as RNA surveillance (Zhu et al., 2005 [PubMed 16024656]). [supplied by OMIM, Mar 2008]. ##Evidence-Data-START## Transcript exon combination :: AK024754.1, AF100786.1 [ECO:0000332] RNAseq introns :: single sample supports all introns ERS025087 [ECO:0000348] ##Evidence-Data-END##
• Synonyms: REC14; SKI8

Reference Data

• Protein Pathways: RNA degradation