ALAS1 Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI1C5]

CAT#: TA808177AM

ALAS1 mouse monoclonal antibody, clone OTI1C5 (formerly 1C5), Biotinylated


USD 420.00

4 Weeks*

Size
    • 100 ug

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Specifications

Product Data
Clone Name OTI1C5
Applications WB
Recommended Dilution WB 1:2000
Reactivities Human, Mouse, Rat
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Human recombinant protein fragment corresponding to amino acids 57-308 of human ALAS1(NP_000679) produced in E.coli.
Formulation PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 0.5 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Biotin
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 70.4 kDa
Gene Name 5'-aminolevulinate synthase 1
Background This gene encodes the mitochondrial enzyme which is catalyzes the rate-limiting step in heme (iron-protoporphyrin) biosynthesis. The enzyme encoded by this gene is the housekeeping enzyme; a separate gene encodes a form of the enzyme that is specific for erythroid tissue. The level of the mature encoded protein is regulated by heme: high levels of heme down-regulate the mature enzyme in mitochondria while low heme levels up-regulate. A pseudogene of this gene is located on chromosome 12. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Dec 2011]
Synonyms ALAS; ALAS-H; ALAS3; ALASH; MIG4
Reference Data
Protein Pathways Glycine, serine and threonine metabolism, Metabolic pathways, Porphyrin and chlorophyll metabolism

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.