ERCC8 Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI9B11]
CAT#: TA808562AM
ERCC8 mouse monoclonal antibody, clone OTI9B11 (formerly 9B11), Biotinylated
Other products for "ERCC8"
Specifications
Product Data | |
Clone Name | OTI9B11 |
Applications | WB |
Recommended Dilution | WB 1:2000 |
Reactivities | Human, Mouse, Rat |
Host | Mouse |
Isotype | IgG2b |
Clonality | Monoclonal |
Immunogen | Full length human recombinant protein of human ERCC8(NP_001007235) produced in E.coli. |
Formulation | PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | 0.5 mg/ml |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Biotin |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 43.9 kDa |
Gene Name | ERCC excision repair 8, CSA ubiquitin ligase complex subunit |
Database Link | |
Background | This gene encodes a WD repeat protein, which interacts with Cockayne syndrome type B (CSB) protein and with p44 protein, a subunit of the RNA polymerase II transcription factor IIH. Mutations in this gene have been identified in patients with hereditary disease Cockayne syndrome (CS). CS cells are abnormally sensitive to ultraviolet radiation and are defective in the repair of transcriptionally active genes. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2014] |
Synonyms | CKN1; CSA; UVSS2 |
Reference Data | |
Protein Families | Druggable Genome, Transcription Factors |
Protein Pathways | Nucleotide excision repair, Ubiquitin mediated proteolysis |
Documents
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