Estrogen Receptor 1 (ESR1) Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI5E11]

CAT#: TA809106BM

ESR1 mouse monoclonal antibody, clone OTI5E11 (formerly 5E11), HRP conjugated


USD 420.00

4 Weeks*

Size
    • 100 ug

Other products for "ESR1"

Specifications

Product Data
Clone Name OTI5E11
Applications IHC, WB
Recommended Dilution WB 1:200~2000, IHC 1:150
Reactivities Human, Mouse, Rat, Dog
Host Mouse
Isotype IgG2a
Clonality Monoclonal
Immunogen Human recombinant protein fragment corresponding to amino acids 1-310 of human ESR1 (NP_000116) produced in E.coli.
Formulation PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 0.5 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation HRP
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 66 kDa
Gene Name estrogen receptor 1
Background This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative promoter usage and alternative splicing result in dozens of transcript variants, but the full-length nature of many of these variants has not been determined. [provided by RefSeq, Mar 2014]
Synonyms ER; Era; ESR; ESRA; ESTRR; NR3A1
Reference Data
Protein Families Druggable Genome, Nuclear Hormone Receptor, Transcription Factors

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.