OTX2 Mouse Monoclonal Antibody [Clone ID: OTI2B3]
CAT#: TA809510S
OTX2 mouse monoclonal antibody,clone OTI2B3
Size: 100 ul
View other "OTI2B3" antibodies (2)
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Specifications
Product Data | |
Clone Name | OTI2B3 |
Applications | IHC, WB |
Recommended Dilution | WB 1:2000, IHC 1:500 |
Reactivities | Human, Mouse, Rat |
Host | Mouse |
Isotype | IgG2b |
Clonality | Monoclonal |
Immunogen | Full length human recombinant protein of human OTX2 (NP_068374) produced in E.coli. |
Formulation | PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | 1 mg/ml |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 32.2 kDa |
Gene Name | orthodenticle homeobox 2 |
Database Link | |
Background | This gene encodes a member of the bicoid subfamily of homeodomain-containing transcription factors. The encoded protein acts as a transcription factor and plays a role in brain, craniofacial, and sensory organ development. The encoded protein also influences the proliferation and differentiation of dopaminergic neuronal progenitor cells during mitosis. Mutations in this gene cause syndromic microphthalmia 5 (MCOPS5) and combined pituitary hormone deficiency 6 (CPHD6). This gene is also suspected of having an oncogenic role in medulloblastoma. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Pseudogenes of this gene are known to exist on chromosomes two and nine. [provided by RefSeq, Jul 2012] |
Synonyms | CPHD6; MCOPS5 |
Reference Data | |
Protein Families | Embryonic stem cells, Induced pluripotent stem cells, Stem cell - Pluripotency, Transcription Factors |
Documents
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