NAT1 Mouse Monoclonal Antibody [Clone ID: OTI4E9]

CAT#: TA810654S

NAT1 mouse monoclonal antibody,clone OTI4E9

Product Images

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY NAT1 (RC221042, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-NAT1 (1:2000). Positive lysates LY424588 (100ug) and LC424588 (20ug) can be purchased separately from OriGene.

Specifications

Product Data

• Clone Name: OTI4E9
• Applications: WB
• Recommended Dilution: WB 1:2000
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Full length human recombinant protein of human NAT1 (NP_000653) produced in E.coli.
• Formulation: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: N-acetyltransferase 1 (arylamine N-acetyltransferase)
• Database Link:
  NP_000653
  Entrez Gene 9 Human
  UniProt ID P18440
• Background: This gene is one of two arylamine N-acetyltransferase (NAT) genes in the human genome, and is orthologous to the mouse and rat Nat2 genes. The enzyme encoded by this gene catalyzes the transfer of an acetyl group from acetyl-CoA to various arylamine and hydrazine substrates. This enzyme helps metabolize drugs and other xenobiotics, and functions in folate catabolism. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]
• Synonyms: AAC1; MNAT; NAT-1; NATI

Reference Data

• Protein Pathways: Caffeine metabolism, Drug metabolism - other enzymes, Metabolic pathways