HOXD8 Mouse Monoclonal Antibody [Clone ID: OTI1E3]

CAT#: TA810941

HOXD8 mouse monoclonal antibody,clone OTI1E3

Product Images

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY HOXD8 (RC205062, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-HOXD8. Positive lysates LY412699 (100ug) and LC412699 (20ug) can be purchased separately from OriGene.

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  Western blot analysis of extracts (35ug) from 3 cell lines by using anti-HOXD8 monoclonal antibody (1:500).

Specifications

Product Data

• Clone Name: OTI1E3
• Applications: WB
• Recommended Dilution: WB 1:500~2000
• Reactivities: Human, Mouse
• Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: Human recombinant protein fragment corresponding to amino acids 69-290 of human HOXD8 (NP_062458) produced in E.coli.
• Formulation: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 31.7 kDa
• Gene Name: homeobox D8
• Database Link:
  NP_062458
  Entrez Gene 3234 Human
  UniProt ID P13378
• Background: This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located in a cluster on chromosome 2. Deletions that remove the entire HOXD gene cluster or the 5' end of this cluster have been associated with severe limb and genital abnormalities. In addition to effects during embryogenesis, this particular gene may also play a role in adult urogenital tract function. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Dec 2010]
• Synonyms: HOX4; HOX4E; HOX5.4

Reference Data

• Protein Families: ES Cell Differentiation/IPS, Transcription Factors