GRK1 Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI4G8]

CAT#: TA811857AM

GRK1 mouse monoclonal antibody,clone OTI4G8, Biotinylated

Product Images

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY GRK1 (RC214569, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-GRK1. Positive lysates LY419010 (100ug) and LC419010 (20ug) can be purchased separately from OriGene.

Specifications

Product Data

• Clone Name: OTI4G8
• Applications: WB
• Recommended Dilution: WB 1:2000
• Reactivities: Human, Mouse, Rat
• Host: Mouse
• Isotype: IgG2b
• Clonality: Monoclonal
• Immunogen: Full length human recombinant protein of human GRK1 (NP_002920) produced in HEK293T cell.
• Formulation: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
• Concentration: 0.5 mg/ml
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Biotin
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 63.3 kDa
• Gene Name: G protein-coupled receptor kinase 1
• Database Link:
  NP_002920
  Entrez Gene 24013 MouseEntrez Gene 81760 RatEntrez Gene 6011 Human
  UniProt ID Q15835
• Background: This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates rhodopsin and initiates its deactivation. Defects in GRK1 are known to cause Oguchi disease 2 (also known as stationary night blindness Oguchi type-2). [provided by RefSeq, Jul 2008]
• Synonyms: GPRK1; RHOK; RK

Reference Data

• Protein Families: Druggable Genome, Protein Kinase
• Protein Pathways: Chemokine signaling pathway, Endocytosis