Drebrin (DBN1) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI1B8]

CAT#: TA812125AM

DBN1 mouse monoclonal antibody,clone OTI1B8, Biotinylated

Product Images

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY DBN1 (RC200372, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-DBN1. Positive lysates LY418021 (100ug) and LC418021 (20ug) can be purchased separately from OriGene.

Specifications

Product Data

• Clone Name: OTI1B8
• Applications: WB
• Recommended Dilution: WB 1:2000
• Reactivities: Human, Mouse, Rat
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Human recombinant protein fragment corresponding to amino acids 2-240 of human DBN1 (NP_004386) produced in E.coli.
• Formulation: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
• Concentration: 0.5 mg/ml
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Biotin
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 71.3 kDa
• Gene Name: drebrin 1
• Database Link:
  NP_004386
  Entrez Gene 56320 MouseEntrez Gene 1627 Human
  UniProt ID Q16643
• Background: The protein encoded by this gene is a cytoplasmic actin-binding protein thought to play a role in the process of neuronal growth. It is a member of the drebrin family of proteins that are developmentally regulated in the brain. A decrease in the amount of this protein in the brain has been implicated as a possible contributing factor in the pathogenesis of memory disturbance in Alzheimer's disease. At least two alternative splice variants encoding different protein isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
• Synonyms: D0S117E