Collagen III (COL3A1) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI2G3]

CAT#: TA812161AM

COL3A1 mouse monoclonal antibody,clone OTI2G3, Biotinylated

Product Images

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY COL3A1 (RC211766, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-COL3A. Positive lysates LY400026 (100ug) and LC400026 (20ug) can be purchased separately from OriGene.

Specifications

Product Data

• Clone Name: OTI2G3
• Applications: WB
• Recommended Dilution: WB 1:500
• Reactivities: Human, Mouse, Rat
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Human recombinant protein fragment corresponding to amino acids 981-1205 of human COL3A1 (NP_000081) produced in E.coli.
• Formulation: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
• Concentration: 0.5 mg/ml
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Biotin
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 138.56 kDa
• Gene Name: collagen type III alpha 1 chain
• Database Link:
  NP_000081
  Entrez Gene 12825 MouseEntrez Gene 84032 RatEntrez Gene 1281 Human
  UniProt ID P02461
• Background: This gene encodes the pro-alpha1 chains of type III collagen, a fibrillar collagen that is found in extensible connective tissues such as skin, lung, uterus, intestine and the vascular system, frequently in association with type I collagen. Mutations in this gene are associated with Ehlers-Danlos syndrome types IV, and with aortic and arterial aneurysms. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. [provided by R. Dalgleish, Feb 2008]
• Synonyms: EDS4A

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: ECM-receptor interaction, Focal adhesion