GRB10 Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI6G1]
Other products for "GRB10"
Specifications
Product Data | |
Clone Name | OTI6G1 |
Applications | WB |
Recommended Dilution | WB 1:500 |
Reactivities | Human, Mouse, Rat |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Human recombinant protein fragment corresponding to amino acids 164-415 of human GRB10 (NP_005302) produced in E.coli. |
Formulation | PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | 0.5 mg/ml |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Biotin |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 67.1 kDa |
Gene Name | growth factor receptor bound protein 10 |
Database Link | |
Background | The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors. Overexpression of some isoforms of the encoded protein inhibits tyrosine kinase activity and results in growth suppression. This gene is imprinted in a highly isoform- and tissue-specific manner, with expression observed from the paternal allele in the brain, and from the maternal allele in the placental trophoblasts. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Oct 2010] |
Synonyms | Grb-10; GRB-IR; IRBP; MEG1; RSS |
Reference Data | |
Protein Families | Druggable Genome |
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