TNFRSF4 Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI7H9]

CAT#: TA812430AM

TNFRSF4 mouse monoclonal antibody,clone OTI7H9, Biotinylated

Product Images

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TNFRSF4 (RC211253, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-TNFRSF4 (1:1000).

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  Flow cytometric analysis of living 293T cells transfected with TNFRSF4 overexpression plasmid (RC211253), Red)/empty vector (PS100001, Blue) using anti-TNFRSF4 antibody (TA812430). Cells incubated with a non-specific antibody (Green) were used as isotype control (1:100).

Specifications

Product Data

• Clone Name: OTI7H9
• Applications: FC, WB
• Recommended Dilution: WB 1:1000, FLOW 1:100
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Full length human recombinant protein of human TNFRSF4 (NP_003318) produced in HEK293T cell.
• Formulation: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
• Concentration: 0.5 mg/ml
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Biotin
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 29.34 kDa
• Gene Name: tumor necrosis factor receptor superfamily member 4
• Database Link:
  NP_003318
  Entrez Gene 7293 Human
  UniProt ID P43489
• Background: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation. [provided by RefSeq, Jul 2008]
• Synonyms: ACT35; CD134; IMD16; OX40; TXGP1L

Reference Data

• Protein Families: Transmembrane
• Protein Pathways: Cytokine-cytokine receptor interaction