Bim (BCL2L11) Mouse Monoclonal Antibody [Clone ID: OTI2H5]

CAT#: TA812441S

BCL2L11 mouse monoclonal antibody,clone OTI2H5

Size: 30 ul 100 ul


  View other "OTI2H5" antibodies (2)

USD 159.00

In Stock*

Size
    • 30 ul

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Frequently bought together (2)
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Specifications

Product Data
Clone Name OTI2H5
Applications WB
Recommended Dilution WB 1:500
Reactivities Human, Mouse, Rat
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Human recombinant protein fragment corresponding to amino acids 1-198 of human BCL2L11 (NP_619527) produced in E.coli.
Formulation PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 1 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Gene Name BCL2 like 11
Background The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains a Bcl-2 homology domain 3 (BH3). It has been shown to interact with other members of the BCL-2 protein family and to act as an apoptotic activator. The expression of this gene can be induced by nerve growth factor (NGF), as well as by the forkhead transcription factor FKHR-L1, which suggests a role of this gene in neuronal and lymphocyte apoptosis. Transgenic studies of the mouse counterpart suggested that this gene functions as an essential initiator of apoptosis in thymocyte-negative selection. Several alternatively spliced transcript variants of this gene have been identified. [provided by RefSeq, Jun 2013]
Synonyms BAM; BIM; BOD
Reference Data
Protein Families Druggable Genome

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