HB EGF (HBEGF) Mouse Monoclonal Antibody [Clone ID: OTI6F4]

CAT#: TA812466S

HBEGF mouse monoclonal antibody,clone OTI6F4

Size: 30 ul 100 ul


  View other "OTI6F4" antibodies (2)

USD 159.00

2 Days*

Size
    • 30 ul

Product Images

Frequently bought together (4)
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Specifications

Product Data
Clone Name OTI6F4
Applications WB
Recommended Dilution WB 1:2000
Reactivities Human
Host Mouse
Isotype IgG2b
Clonality Monoclonal
Immunogen Human recombinant protein fragment corresponding to amino acids 20-208 of human HBEGF (NP_001936) produced in E.coli.
Formulation PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 1 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 22.9 kDa
Gene Name heparin binding EGF like growth factor
Background Growth factor that mediates its effects via EGFR, ERBB2 and ERBB4. Required for normal cardiac valve formation and normal heart function. Promotes smooth muscle cell proliferation. May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts, but not endothelial cells. It is able to bind EGF receptor/EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. Also acts as a diphtheria toxin receptor. [UniProtKB/Swiss-Prot Function]
Synonyms DTR; DTS; DTSF; HEGFL
Reference Data
Protein Families Druggable Genome, Secreted Protein, Transmembrane
Protein Pathways Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, GnRH signaling pathway

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.