CD70 Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI7B2]

CAT#: TA813205AM

CD70 mouse monoclonal antibody,clone OTI7B2, Biotinylated

Product Images

Flow cytometric analysis of living 293T cells transfected with CD70 overexpression plasmid (RC200410), Red)/empty vector (PS100001, Blue) using anti-CD70 antibody (TA813205). Cells incubated with a non-specific antibody (Green) were used as isotype control (1:100).

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  Flow cytometric analysis of living Raji cells, using anti-CD70 antibody (TA813205, Red), compared to an isotype control (green), and a PBS control (blue) (1:100).

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  Flow cytometric analysis of living 786-O cells, using anti-CD70 antibody (TA813205, Red), compared to an isotype control (green), and a PBS control (blue) (1:100).

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  Flow cytometric analysis of living PBMCs treated with 10ug/ml PHA for 72h (Right)/untreated (Left) using anti-CD70 antibody (TA813205) (1:100).

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  Flow cytometric analysis of living PBMCs treated with 10ug/ml PHA for 72h using anti-CD70 antibody (TA813205) (Right). Cells incubated with a non-specific antibody (Left) were used as isotype control (1:100).

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Specifications

Product Data

• Clone Name: OTI7B2
• Applications: FC
• Recommended Dilution: FLOW 1:100
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Full length human recombinant protein of human CD70 (NP_001243) produced in HEK293T cell.
• Formulation: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
• Concentration: 0.5 mg/ml
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Biotin
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 20.9 kDa
• Gene Name: CD70 molecule
• Database Link:
  NP_001243
  Entrez Gene 970 Human
  UniProt ID P32970
• Background: Cytokine that binds to CD27. Plays a role in T-cell activation. Induces the proliferation of costimulated T-cells and enhances the generation of cytolytic T-cells. [UniProtKB/Swiss-Prot Function]
• Synonyms: CD27-L; CD27L; CD27LG; LPFS3; TNFSF7; TNLG8A

Reference Data

• Protein Families: ES Cell Differentiation/IPS, Transmembrane
• Protein Pathways: Cytokine-cytokine receptor interaction