ICOS Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI5G8]

CAT#: TA813212AM

ICOS mouse monoclonal antibody,clone OTI5G8, Biotinylated

Product Images

Flow cytometric analysis of living 293T cells transfected with ICOS overexpression plasmid (RC207031), Red)/empty vector (PS100001, Blue) using anti-ICOS antibody (TA813212). Cells incubated with a non-specific antibody (Green) were used as isotype control (1:400).

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  Flow cytometric analysis of living PBMCs treated with 10ug/ml PHA for 72h (Right)/untreated (Left) using anti-ICOS antibody (TA813212) (1:100).

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  Flow cytometric analysis of living PBMCs treated with 10ug/ml PHA for 72h using anti-ICOS antibody (TA813212) (Right). Cells incubated with a non-specific antibody (Left) were used as isotype control (1:100).

Specifications

Product Data

• Clone Name: OTI5G8
• Applications: FC
• Recommended Dilution: FLOW 1:100~400
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Full length human recombinant protein of human ICOS (NP_036224) produced in HEK293T cell.
• Formulation: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
• Concentration: 0.5 mg/ml
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Biotin
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 20.2 kDa
• Gene Name: inducible T-cell costimulator
• Database Link:
  NP_036224
  Entrez Gene 29851 Human
  UniProt ID Q9Y6W8
• Background: The protein encoded by this gene belongs to the CD28 and CTLA-4 cell-surface receptor family. It forms homodimers and plays an important role in cell-cell signaling, immune responses, and regulation of cell proliferation. [provided by RefSeq, Jul 2008]
• Synonyms: AILIM; CD278; CVID1

Reference Data

• Protein Families: Secreted Protein, Transmembrane
• Protein Pathways: Cell adhesion molecules (CAMs), Primary immunodeficiency, T cell receptor signaling pathway