Syndecan 1 (SDC1) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI7H2]

CAT#: TA813775AM

SDC1 mouse monoclonal antibody, clone OTI7H2, Biotinylated

Product Images

Flow cytometric analysis of living 293T cells transfected with SDC1 overexpression plasmid (RC217847), Red)/empty vector (PS100001, Blue) using anti-SDC1 antibody (TA813775). Cells incubated with a non-specific antibody (Green) were used as isotype control.（1：100）

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  Flow cytometric analysis of living K562 cells, using anti-SDC1 antibody(TA813775, Red), compared to an isotype control (green), and a PBS control (blue).(1:100)

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  Flow cytometric analysis of living RPMI-8226 cells, using anti-SDC1 antibody(TA813775, Red), compared to an isotype control (green), and a PBS control (blue).(1:100)

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  Flow cytometric analysis of living OPM2 cells, using anti-SDC1 antibody(TA813775, Red), compared to an isotype control (green), and a PBS control (blue).(1:100)

Specifications

Product Data

• Clone Name: OTI7H2
• Applications: FC
• Recommended Dilution: FLOW 1:100
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Human recombinant protein fragment corresponding to amino acids 23-254 of human SDC1 (NP_001006947) produced in E.coli.
• Formulation: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
• Concentration: 0.5 mg/ml
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Biotin
• Storage: Shipped at -20°C or with ice packs, Upon delivery store at -20°C. Dilute in PBS(pH7.3) if necessary. Stable for 12 months from date of receipt. Avoid repeated freeze-thaws.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 32.5 kDa
• Gene Name: syndecan 1
• Database Link:
  NP_001006947
  Entrez Gene 6382 Human
  UniProt ID P18827
• Background: The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein. [provided by RefSeq, Jul 2008].
• Synonyms: CD138; SDC; SYND1; syndecan

Reference Data

• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
• Protein Pathways: Cell adhesion molecules (CAMs), ECM-receptor interaction