Caldesmon (CALD1) Mouse Monoclonal Antibody [Clone ID: OTI3E8]
Other products for "CALD1"
Specifications
Product Data | |
Clone Name | OTI3E8 |
Applications | IHC |
Recommended Dilution | IHC1:1200 |
Reactivities | Human |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Human recombinant protein fragment corresponding to amino acids 220-450 human Caldesmon (NP_149129) produced in E.coli. |
Formulation | PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | 1.00mg/ml |
Purification | Purified from mouse ascites fluids by affinity chromatography |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 93.2 kDa |
Gene Name | caldesmon 1 |
Database Link | |
Background | This gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008] |
Synonyms | CDM; H-CAD; HCAD; L-CAD; LCAD; NAG22 |
Reference Data | |
Protein Pathways | Vascular smooth muscle contraction |
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