Desmoplakin (DSP) Rabbit Polyclonal Antibody

CAT#: TA890114

Rabbit Polyclonal anti-DSP Antibody

Product Images

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY DSP (RC220397, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-DSP rabbit polyclonal antibody.

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  Western blot analysis of extracts (35ug) from different cell lines and tissues by using anti-DSP rabbit polyclonal antibody.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500~2000
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant protein of human DSP
• Formulation: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
• Concentration: 2.72 mg/ml
• Purification: Purified from the immunized serum by affinity chromatography (Protein A/G)
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 259.9 kDa
• Gene Name: desmoplakin
• Database Link:
  NP_001008844
  Entrez Gene 306871 RatEntrez Gene 1832 Human
  UniProt ID P15924
• Background: Major high molecular weight protein of desmosomes. Involved in the organization of the desmosomal cadherin-plakoglobin complexes into discrete plasma membrane domains and in the anchoring of intermediate filaments to the desmosomes. [UniProtKB/Swiss-Prot Function]
• Synonyms: DCWHKTA; DP; DPI; DPII

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Arrhythmogenic right ventricular cardiomyopathy (ARVC)