MMP11 Rabbit Polyclonal Antibody

CAT#: TA890134

Rabbit Polyclonal anti-MMP11 Antibody

Product Images

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY MMP11 (RC209223, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-MMP11. Positive lysates LY416967 (100ug) and LC416967 (20ug) can be purchased separately from OriGene.

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  Western blot analysis of extracts (35ug) from different cell lines and tissues by using anti-MMP11 rabbit polyclonal antibody.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500~2000
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant protein of human MMP11
• Formulation: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
• Concentration: 2.04 mg/ml
• Purification: Purified from the immunized serum by affinity chromatography (Protein A/G)
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 54.59 kDa
• Gene Name: matrix metallopeptidase 11
• Database Link:
  NP_005931
  Entrez Gene 17385 MouseEntrez Gene 25481 RatEntrez Gene 4320 Human
  UniProt ID P24347
• Background: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is activated intracellularly by furin within the constitutive secretory pathway. Also in contrast to other MMP's, this enzyme cleaves alpha 1-proteinase inhibitor but weakly degrades structural proteins of the extracellular matrix. [provided by RefSeq, Jul 2008]
• Synonyms: SL-3; ST3; STMY3

Reference Data

• Protein Families: Druggable Genome, Protease