epithelial Sodium Channel alpha (SCNN1A) Rabbit Polyclonal Antibody

CAT#: TA890149

Rabbit Polyclonal anti-SCNN1A Antibody

Size: 30 ul 100 ul


 

USD 345.00

In Stock*

Size
    • 100 ul

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Specifications

Product Data
Applications WB
Recommended Dilution WB: 1:500~2000
Reactivities Human
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Recombinant protein of human SCNN1A
Formulation PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Concentration 1.93 mg/ml
Purification Purified from the immunized serum by affinity chromatography (Protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 75.5 kDa
Gene Name sodium channel epithelial 1 alpha subunit
Background Nonvoltage-gated, amiloride-sensitive, sodium channels control fluid and electrolyte transport across epithelia in many organs. These channels are heteromeric complexes consisting of 3 subunits: alpha, beta, and gamma. This gene encodes the alpha subunit, and mutations in this gene have been associated with pseudohypoaldosteronism type 1 (PHA1), a rare salt wasting disease resulting from target organ unresponsiveness to mineralocorticoids. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Apr 2009]
Synonyms BESC2; ENaCa; ENaCalpha; SCNEA; SCNN1
Reference Data
Protein Families Druggable Genome, Ion Channels: Other, Transmembrane
Protein Pathways Taste transduction

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