BubR1 (BUB1B) Mouse Monoclonal Antibody [Clone ID: UMAB7]

CAT#: UM500007

Anti-BUB1B mouse monoclonal antibody, clone UMAB7

Size: 30 ul 100 ul


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USD 468.00

In Stock*

Size
    • 100 ul

Other products for "BUB1B"

Specifications

Product Data
Clone Name UMAB7
Applications IF, IHC, WB
Recommended Dilution WB 1:2000, IHC 1:50, IF 1:100, Flow 1:100, IF 1:100
Reactivities Human, Monkey
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Protein expressed in 293T cell transfected with human BUB1B expression vector
Formulation PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 0.5~1.0 mg/ml (Lot Dependent)
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 119.5 kDa
Gene Name Homo sapiens BUB1 mitotic checkpoint serine/threonine kinase B (BUB1B), mRNA.
Background This gene encodes a kinase involved in spindle checkpoint function. The protein has been localized to the kinetochore and plays a role in the inhibition of the anaphase-promoting complex/cyclosome(APC/C), delaying the onset of anaphase and ensuring proper chromosome segregation. Impaired spindle checkpoint function has been found in many forms of cancer.
Synonyms Bub1A; BUB1beta; BUBR1; hBUBR1; MAD3L; MVA1; SSK1
Reference Data
Protein Families Druggable Genome, Protein Kinase, Stem cell - Pluripotency
Protein Pathways Cell cycle

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