HMBS Mouse Monoclonal Antibody [Clone ID: UMAB144]

CAT#: UM800041

HMBS mouse monoclonal antibody,clone UMAB144

Size: 30 ul 100 ul


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USD 468.00

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Size
    • 100 ul

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Specifications

Product Data
Clone Name UMAB144
Applications IF, IHC, WB
Recommended Dilution WB 1:2000, IHC 1:200
Reactivities Human, Mouse, Rat
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Full length human recombinant protein of human HMBS (NP_000181) produced in HEK293T cell.
Formulation PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 0.5~1.0 mg/ml (Lot Dependent)
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Gene Name Homo sapiens hydroxymethylbilane synthase (HMBS), transcript variant 1, mRNA.
Background This gene encodes a member of the hydroxymethylbilane synthase superfamily. The encoded protein is the third enzyme of the heme biosynthetic pathway and catalyzes the head to tail condensation of four porphobilinogen molecules into the linear hydroxymethylbilane. Mutations in this gene are associated with the autosomal dominant disease acute intermittent porphyria. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
Synonyms PBG-D; PBGD; PORC; UPS
Reference Data
Protein Families Druggable Genome
Protein Pathways Metabolic pathways, Porphyrin and chlorophyll metabolism

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