CDX2 Mouse Monoclonal Antibody [Clone ID: UMAB266]

CAT#: UM800156CF

Carrier-free (BSA/glycerol-free) CDX2 mouse monoclonal antibody,clone UMAB266

Product Images

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-CDX2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer (pH8.0) at 120°C for 2.5 min, UM800156) (1:300)

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  Immunohistochemical staining of paraffin-embedded Human pancreas tissue within the normal limits using anti-CDX2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer (pH8.0) at 120°C for 2.5 min, UM800156) (1:300)

Specifications

Product Data

• Clone Name: UMAB266
• Applications: IHC
• Recommended Dilution: IHC 1:300
• Reactivities: Human, Mouse, Rat
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Full length human recombinant protein of human CDX2 (NP_001256) produced in E.coli.
• Formulation: Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
• Reconstitution Method: For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 33.3 kDa
• Gene Name: Homo sapiens caudal type homeobox 2 (CDX2), transcript variant 1, mRNA.
• Database Link:
  NP_001256
  Entrez Gene 12591 MouseEntrez Gene 66019 RatEntrez Gene 1045 Human
  UniProt ID Q99626
• Background: Involved in the transcriptional regulation of multiple genes expressed in the intestinal epithelium. Important in broad range of functions from early differentiation to maintenance of the intestinal epithelial lining of both the small and large intestine. [UniProtKB/Swiss-Prot Function]
• Synonyms: CDX-3; CDX2/AS; CDX3

Reference Data

• Protein Families: Adult stem cells, Druggable Genome, Embryonic stem cells, ES Cell Differentiation/IPS, Transcription Factors