GBA Mouse Monoclonal Antibody [Clone ID: UMAB171]

CAT#: UM870064

GBA mouse monoclonal antibody,clone UMAB171

Size: 30 ul 100 ul


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USD 180.00

In Stock*

Size
    • 30 ul

Specifications

Product Data
Clone Name UMAB171
Applications 10k-ChIP, IF, IHC
Recommended Dilution IHC 1:100~200
Reactivities Human, Mouse, Rat
Host Mouse
Isotype IgG2a
Clonality Monoclonal
Immunogen Human recombinant protein fragment corresponding to amino acids 40-315 of human GBA (NP_000148) produced in E.coli.
Formulation PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 0.5~1.0 mg/ml (Lot Dependent)
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 55.5 kDa
Gene Name Homo sapiens glucosylceramidase beta (GBA), transcript variant 1, mRNA.
Background This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2010]
Synonyms GBA1; GCB; GLUC
Reference Data
Protein Families Druggable Genome
Protein Pathways Lysosome, Metabolic pathways, Other glycan degradation, Sphingolipid metabolism

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