TNFRSF4 Mouse Monoclonal Antibody [Clone ID: UMAB276]

CAT#: UM870166

OX40(TNFRSF4) mouse monoclonal antibody,clone UMAB276

Size: 30 ul 100 ul


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USD 180.00

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Size
    • 30 ul

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Specifications

Product Data
Clone Name UMAB276
Applications 10k-ChIP, FC, IHC, WB
Recommended Dilution IHC 1:100~300
Reactivities Human
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Full length human recombinant protein of human TNFRSF4 (NP_003318) produced in HEK293T cell.
Formulation PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 0.5~1.0 mg/ml (Lot Dependent)
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 29.34 kDa
Gene Name Homo sapiens TNF receptor superfamily member 4 (TNFRSF4), mRNA.
Background The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation. [provided by RefSeq, Jul 2008]
Synonyms ACT35; CD134; IMD16; OX40; TXGP1L
Reference Data
Protein Families Transmembrane
Protein Pathways Cytokine-cytokine receptor interaction

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