OLIG2 Mouse Monoclonal Antibody [Clone ID: UMAB294]

CAT#: UM870183

OLIG2 mouse monoclonal antibody,clone UMAB294

Product Images

IHC staining of FFPE human adult brain tissue with in the normal limits using anti-OLIG2 mouse monoclonal antibody (UM800183) and Polink-2 HRP polymer detection kit (D22-110). Heat-induced epitope retrieval by EDTA solution buffer pH 8.0 (B04C-100) at 120°C for 3 min. The brown stain indicates positive stain, blue is the counter stain.

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  IHC staining of FFPE human glioma tissue using anti-OLIG2 mouse monoclonal antibody (UM800183) and Polink-2 HRP polymer detection kit (D22-110). Heat-induced epitope retrieval by EDTA solution buffer pH 8.0 (B04C-100) at 120°C for 3 min. The brown stain indicates positive stain, blue is the counter stain.

Specifications

Product Data

• Clone Name: UMAB294
• Applications: IHC
• Recommended Dilution: IHC 1:200
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Human recombinant protein fragment of human OLIG2 (NP_005797) produced in E.coli.
• Formulation: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
• Concentration: 1.00mg/ml
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Unconjugated
• Predicted Protein Size: 32.2 kDa
• Gene Name: oligodendrocyte transcription factor 2
• Database Link:
  NP_005797
  Entrez Gene 10215 Human
  UniProt ID Q13516
• Background: This gene encodes a basic helix-loop-helix transcription factor which is expressed in oligodendroglial tumors of the brain. The protein is an essential regulator of ventral neuroectodermal progenitor cell fate. The gene is involved in a chromosomal translocation t(14;21)(q11.2;q22) associated with T-cell acute lymphoblastic leukemia. Its chromosomal location is within a region of chromosome 21 which has been suggested to play a role in learning deficits associated with Down syndrome. [provided by RefSeq, Jul 2008]
• Synonyms: BHLHB1; bHLHe19; OLIGO2; PRKCBP2; RACK17

Reference Data

• Protein Families: Druggable Genome, Transcription Factors