Calcitonin (CALCA) Mouse Monoclonal Antibody [Clone ID: UMAB303]

CAT#: UM870185

Calcitonin(CALCA) mouse monoclonal antibody,clone UMAB303

Product Images

IHC staining of FFPE human medullary thyroid carcinoma tissue using anti-Calcitonin(CALCA) mouse monoclonal antibody (UM800185) and Polink-2 HRP polymer detection kit (D22-110). Heat-induced epitope retrieval by EDTA solution buffer pH 8.0 (B04C-100) at 120°C for 3 min. The brown stain indicates positive stain, blue is the counter stain.

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  IHC staining of FFPE human papillary thyroid cancer tissue using anti-Calcitonin(CALCA) mouse monoclonal antibody (UM800185) and Polink-2 HRP polymer detection kit (D22-110). Heat-induced epitope retrieval by EDTA solution buffer pH 8.0 (B04C-100) at 120°C for 3 min. The brown stain indicates positive stain, blue is the counter stain.

Specifications

Product Data

• Clone Name: UMAB303
• Applications: IHC
• Recommended Dilution: IHC 1:10000
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human Calcitonin(CALCA) (NP_001732). The exact sequence is proprietary.
• Formulation: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
• Concentration: 1.00mg/ml
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Unconjugated
• Predicted Protein Size: 15.5 kDa
• Gene Name: calcitonin related polypeptide alpha
• Database Link:
  NP_001732
  Entrez Gene 796 Human
  UniProt ID P01258
• Background: This gene encodes the peptide hormones calcitonin, calcitonin gene-related peptide and katacalcin by tissue-specific alternative RNA splicing of the gene transcripts and cleavage of inactive precursor proteins. Calcitonin is involved in calcium regulation and acts to regulate phosphorus metabolism. Calcitonin gene-related peptide functions as a vasodilator and as an antimicrobial peptide while katacalcin is a calcium-lowering peptide. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Aug 2014]
• Synonyms: CALC1; CGRP; CGRP-alpha; CGRP-I; CGRP1; CT; KC; PCT

Reference Data

• Protein Families: Druggable Genome, Secreted Protein