Human Perforin ELISA Set, 10 x 96-well

CAT#: EA101394

Human Perforin ELISA Set, 10 x 96-well

Specifications

Product Data

• Format: 10 x 96-well
• Assay Type: Solid Phase Sandwich ELISA
• Assay Length: From sample to end 3h45min
• Signal: Colorimetric
• Curve Range: 62.5-2000 pg/ml
• Sample Type: Serum, Plasma, Cell culture supernatant
• Sample Volume: 100 µl
• Specificity: Recognizes both natural and recombinant human Perforin
• Sensitivity: 40 pg/ml
• Cross Reactivity: No cross reactivity with other human soluble molecules
• Components: ELISA Sets include capture and biotinylated detection antibody, one standard per plate, Streptavidin-HRP, TMB, and detailed procedure including buffer composition.
• Background: The protein encoded by this gene has structural and functional similarities to complement component 9 (C9). Like C9, this protein creates transmembrane tubules and is capable of lysing non-specifically a variety of target cells. This protein is one of the main cytolytic proteins of cytolytic granules, and it is known to be a key effector molecule for T-cell- and natural killer-cell-mediated cytolysis. Defects in this gene cause familial hemophagocytic lymphohistiocytosis type 2 (HPLH2), a rare and lethal autosomal recessive disorder of early childhood. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]
• Gene Symbol: PRF1