Human Perforin ELISA Set, 10 x 96-well

CAT#: EA101394

Human Perforin ELISA Set, 10 x 96-well


USD 470.00

3 Weeks*

Size
    • 10 x 96 wells

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Specifications

Product Data
Format 10 x 96-well
Assay Type Solid Phase Sandwich ELISA
Assay Length From sample to end 3h45min
Signal Colorimetric
Curve Range 62.5-2000 pg/ml
Sample Type Serum, Plasma, Cell culture supernatant
Sample Volume 100 µl
Specificity Recognizes both natural and recombinant human Perforin
Sensitivity 40 pg/ml
Cross Reactivity No cross reactivity with other human soluble molecules
Components ELISA Sets include capture and biotinylated detection antibody, one standard per plate, Streptavidin-HRP, TMB, and detailed procedure including buffer composition.
Background The protein encoded by this gene has structural and functional similarities to complement component 9 (C9). Like C9, this protein creates transmembrane tubules and is capable of lysing non-specifically a variety of target cells. This protein is one of the main cytolytic proteins of cytolytic granules, and it is known to be a key effector molecule for T-cell- and natural killer-cell-mediated cytolysis. Defects in this gene cause familial hemophagocytic lymphohistiocytosis type 2 (HPLH2), a rare and lethal autosomal recessive disorder of early childhood. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]
Gene Symbol PRF1

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.