Human Perforin ELISpot Kit, 1 x 96-well (pre-coated plate)

CAT#: EA101618

Human Perforin ELISpot Kit, 1 x 96-well (pre-coated plate)


USD 290.00

3 Weeks*

Size
    • 1 x 96 wells (pre-coated plate)

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Specifications

Product Data
Format 1 x 96-well (pre-coated plate)
Assay Type Enzyme-Linked ImmunoSpot (ELISpot)
Assay Length 3h after cell stimulation
Signal Colorimetric
Specificity Recognizes natural human Perforin
Components Pre-coated ELISpot kits include precoated PVDF plates, Detection antibody, Alkaline phosphatase conjugate, BSA, BCIP/NBT ready-to-use substrate buffer.
Background The protein encoded by this gene has structural and functional similarities to complement component 9 (C9). Like C9, this protein creates transmembrane tubules and is capable of lysing non-specifically a variety of target cells. This protein is one of the main cytolytic proteins of cytolytic granules, and it is known to be a key effector molecule for T-cell- and natural killer-cell-mediated cytolysis. Defects in this gene cause familial hemophagocytic lymphohistiocytosis type 2 (HPLH2), a rare and lethal autosomal recessive disorder of early childhood. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]
Gene Symbol PRF1

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.