Human Cytokeratin 19 (KRT19) ELISA Kit 1 x 96

CAT#: EA200024

Human Cytokeratin 19 (KRT19) ELISA Kit 1 x 96

Product Images

Data image of Cytokeratin 19 (KRT19) ELISA Kit.

Specifications

Product Data

• Format: 8x12 divisible strips
• Assay Type: Sandwich
• Assay Length: 4 hours incubations; 30min washing and analyzing samples
• Signal: Colorimetric
• Curve Range: 15.6pg/ml-1000pg/ml
• Sample Type: Human serum, plasma and other biological fluids
• Sample Volume: 100µl
• Specificity: This kit is used for quantitative detection of Human KRT19
• Sensitivity: 8pg/ml
• Reactivities: Human
• Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.
• Interference: No significant interference observed with available related molecules.
• Components:
  • KRT19 Antibody Coated 96-well Plate in foil pouch with desiccant|1 plate
  • Recombinant HumanKRT19 Standard (50ng/ml)|0.1 mL
  • 100x Biotinylated Human KRT19 Detection Antibody|0.12 mL
  • 100x Peroxidase Conjugate|0.12 mL
  • Assay Buffer|60 mL
  • Wash Buffer Concentrate 20X|60 mL
  • TMB Substrate|12 mL
  • Stop Solution|12 mL
• Background: Keratin-19 (KRT19) also known as keratin, type I cytoskeletal 19, cytokeratin-19 (CK-19), or CYFRA 21-1, is a 40 kDa protein that in humans is encoded by the KRT19 gene. Keratin 19 is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Keratin 19 is a type I keratin. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. KRT19 is the most used marker for the RT-PCR-mediated detection of tumor cells disseminated in lymph nodes, peripheral blood, and bone marrow of breast cancer patients. There is a positive correlation between higher expression of KRT19 in some kind of cancers and worse patient survival, where it serves as a diagnostic or prognostic biomarker.
• Gene Symbol: KRT19
• Gene ID: 3880
• Standard Curve:
  
  Data image of Cytokeratin 19 (KRT19) ELISA Kit.