FNDC4 (NM_022823) Human 3' UTR Clone

CAT#: SC207774

3`UTR clone of fibronectin type III domain containing 4 (FNDC4) for miRNA target validation

Specifications

Product Data

• Vector: pMirTarget
• Species: Human
• Transfection Reporter: RFP
• Assay Reporter: Luciferase
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Symbol: FNDC4
• Synonyms: FRCP1
• ACCN: NM_022823
• Insert Size: 578
• Sequence Data:
  Insert Sequence

  >SC207774 3'UTR clone of NM_022823
  The sequence shown below is from the reference sequence of NM_022823. The complete sequence of this clone may contain minor differences, such as SNPs. Red=Cloning site Blue=Stop Codon
  
  
  CAATTGGCAGAGCTCAGAATTCAAGCGATCGC
  
  CAACACCATCGACGTTTGAGTGAAGAAACACACCCAGAAGAGAGATGCACTAACAACTGGGGATAGGGAT
  GGGGTCAGGGGGAGCCCAAGATGGTGATCTGCCCGAGACTCCCAGAGGGTAATGCCACTCCCACAATCTC
  AGGCCTGGTACCCATCCTCTTTCCACTGTGAGCAGAGCCAGAAGGTAGGTCTGTTCAGAGTCTGTGCCCC
  TGGACCTGGGGAGTGGATATCAGATGGGATATCTCCTTCCATTCCCCGGTCCAGGGGAGAGTCACTAGTT
  GTACCCTACTCCATTAGGTCCCAAATGGGGGCCCCATTTCACCTGTATCAGGACTCTGAGCATCCCCAGC
  TGCCCCACATCTTGCCTCTGGCCCTCAGAGAGGGGTGTTTCTGTGGGTACTCCTCTTACCCCAGCAAATA
  AAAGGAATTGTCTGACCCTAGAGGCAGATGCTGCACTGCACTACTCCAATGTCTTCCATGGAGCCTCAGG
  TGCTCCCCCTCTCACCTGGCAGCCCCTTCAGCTGCTAGTGATATCACTTGTTGGACATTTTTCCAATAAA
  GGTTCTTGGACAAACTGG
  
  ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCG
• Restriction Sites: SgfI-MluI
• OTI Disclaimer: Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).

Reference Data

• RefSeq: NM_022823.2
• Summary: Acts as an anti-inflammatory factor in the intestine and colon. Binds to and acts on macrophages to downregulate pro-inflammatory gene expression. Affects key macrophage functions, including phagocytosis, by downregulating many key pathways for macrophage activation, partly via by STAT3 activation and signaling. May be required to dampen the immunological response in colitis. [UniProtKB/Swiss-Prot Function]
• Locus ID: 64838