IL18BP (NM_173042) Human 3' UTR Clone

CAT#: SC208856

3`UTR clone of interleukin 18 binding protein (IL18BP) transcript variant A for miRNA target validation

Specifications

Product Data

• Vector: pMirTarget
• Species: Human
• Transfection Reporter: RFP
• Assay Reporter: Luciferase
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Symbol: IL18BP
• Synonyms: IL18BPa
• ACCN: NM_173042
• Insert Size: 686
• Sequence Data:
  Insert Sequence

  >SC208856 3'UTR clone of NM_173042
  The sequence shown below is from the reference sequence of NM_173042. The complete sequence of this clone may contain minor differences, such as SNPs. Red=Cloning site Blue=Stop Codon
  
  
  CAATTGGCAGAGCTCAGAATTCAAGCGATCGC
  
  TCCAGCCACAGCAGTCCACAGCAGCAGGGTTAAGACTCAGCACAGGGCCAGCAGCAGCACAACCTTGACC
  AGAGCTTGGGTCCTACCTGTCTACCTGGAGTGAACAGTCCCTGACTGCCTGTAGGCTGCGTGGATGCGCA
  ACACACCCCCTCCTTCTCTGCTTTGGGTCCCTTCTCTCACCAAATTCAAACTCCATTCCCACCTACCTAG
  AAAATCACAGCCTCCTTATAATGCCTCCTCCTCCTGCCATTCTCTCTCCACCTATCCATTAGCCTTCCTA
  ACGTCCTACTCCTCACACTGCTCTACTGCTCAGAAACCACCAAGACTGTTGATGCCTTAGCCTTGCACTC
  CAGGGCCCTACCTGCATTTCCCACATGACTTTCTGGAAGCCTCCCAACTATTCTTGCTTTTCCCAGACAG
  CTCCCACTCCCATGTCTCTGCTCATTTAGTCCCGTCTTCCTCACCGCCCCAGCAGGGGAACGCTCAAGCC
  TGGTTGAAATGCTGCCTCTTCAGTGAAGTCATCCTCTTTCAGCTCTGGCCGCATTCTGCAGACTTCCTAT
  CTTCGTGCTGTATGTTTTTTTTTTCCCCCTTCACTCTAATGGACTGTTCCAGGGAAGGGATGGGGGCAGC
  AGCTGCTTCGGATCCACACTGTATCTGTGTCATCCCCACATGGGTCCTCATAAAGG
  
  ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCG
• Restriction Sites: SgfI-MluI
• OTI Disclaimer: Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).

Reference Data

• RefSeq: NM_173042.2
• Summary: The protein encoded by this gene functions as an inhibitor of the proinflammatory cytokine, IL18. It binds IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production, resulting in reduced T-helper type 1 immune responses. This protein is constitutively expressed and secreted in mononuclear cells. Elevated level of this protein is detected in the intestinal tissues of patients with Crohn's disease. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2011]
• Locus ID: 10068