ABCB11 (NM_003742) Human 3' UTR Clone

CAT#: SC208868

3`UTR clone of ATP-binding cassette sub-family B (MDR/TAP) member 11 (ABCB11) for miRNA target validation

Specifications

Product Data

• Vector: pMirTarget
• Species: Human
• Transfection Reporter: RFP
• Assay Reporter: Luciferase
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Symbol: ABCB11
• Synonyms: ABC16; BRIC2; BSEP; PFIC-2; PFIC2; PGY4; SPGP
• ACCN: NM_003742
• Insert Size: 703
• Sequence Data:
  Insert Sequence

  >SC208868 3'UTR clone of NM_003742
  The sequence shown below is from the reference sequence of NM_003742. The complete sequence of this clone may contain minor differences, such as SNPs. Red=Cloning site Blue=Stop Codon
  
  
  CAATTGGCAGAGCTCAGAATTCAAGCGATCGC
  
  ACTAGTCACCACTGGATCCCCCATCAGTTGACCCAATGCAAGAATCTCAGACACACATGACGCACCAGTT
  ACAGGGGTTGTTTTTAAAGAAAAAAACAATCCCAGCAGGAGGGATTGCTGGGATTGTTTTTTCTTTAAAG
  AAGAATGTTAATATTTTACTTTTACAGTCATTTTCCTACATCGGAATCCAAGCTAATTTCTAATGGCCTT
  CCATAATAATTCTGCTTTAGATGTGTATACAGAAAATGAAAGAAACTAGGGTCCATATGAGGGAAAACCC
  AATGTCAAGTGGCAGCTCAGCCACCACTCAGTGCTTCTCTGTGCAGGAGCCAGTCCTGATTAATATGTGG
  GAATTAGTGAGACATCAGGGAGTAAGTGACACTTTGAACTCCTCAAGGGCAGAGAACTGTCTTTCATTTT
  TGAACCCTCGGTGTACACAGAGGCGGGTCTATAACAGGCAATCAACAAACGTTTCTTGAGCTAGACCAAG
  GTCAGATTTGAAAAGAACAGAAGGACTGAAGACCAGCTGTGTTTCTTAACTAAATTTGTCTTTCAAGTGA
  AACCAGCTTCCTTCATCTCTAAGGCTAAGGATAGGGAAAGGGTGGATGCTCTCAGGCTGAGGGAGGCAGA
  AAGGGAAAGTATTAGCATGAGCTTTCCAGTTAGGGCTGTTGATTTATGCTTTAACTTCAGAGTGAGTGTA
  GGG
  
  ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCG
• Restriction Sites: SgfI-MluI
• OTI Disclaimer: Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).

Reference Data

• RefSeq: NM_003742.2
• Summary: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is the major canalicular bile salt export pump in man. Mutations in this gene cause a form of progressive familial intrahepatic cholestases which are a group of inherited disorders with severe cholestatic liver disease from early infancy. [provided by RefSeq, Jul 2008]
• Locus ID: 8647