COX7A2L (NM_004718) Human 3' UTR Clone
CAT#: SC209491
3`UTR clone of cytochrome c oxidase subunit VIIa polypeptide 2 like (COX7A2L) nuclear gene encoding mitochondrial protein for miRNA target validation
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Specifications
Product Data | |
Vector | pMirTarget |
Species | Human |
Transfection Reporter | RFP |
Assay Reporter | Luciferase |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Symbol | COX7A2L |
Synonyms | COX7AR; COX7RP; EB1; SIG81 |
ACCN | NM_004718 |
Insert Size | 746 |
Sequence Data |
>SC209491 3'UTR clone of NM_004718
The sequence shown below is from the reference sequence of NM_004718. The complete sequence of this clone may contain minor differences, such as SNPs. Red=Cloning site Blue=Stop Codon CAATTGGCAGAGCTCAGAATTCAAGCGATCGC CCTCTACATGGCTTCGCAGCCCAAAAACAAATGAGTTAGGCTGCAGAGGACTGGTTTGTTTTTTGGCATA AACCCTTTGAAGTTCCTTTTTCATTGTTAAATTAAAATTTTTTTTTTTACTTGGATGGCTTAACATTTTT GCAAGAAAAATAGGAAGATATGAAGATGATGTTTTGGTTTGTTTATGAAATGCATATGGCTTGTCAGAGC TCATTCGACAGTTAAAGCCATTGTTTAAAGAAATGGTGCTTTGCTCTGTGTTTGTGCTCCTGATTTCCCT GGAGGTTCTGGATGAAGGCTGAACACAGGCTTGTTAATGTCAGTCTGTGCTGAGGACCTCAGGGACTTGA GGTTGCATTTTTGAGCATGGGGTGCAGGAGCCTTTCTGGATTTGGATGTGGCTATGGAAAGAACACAGAA GCCAAGGTCATGTGCATGAAATGAGGAGTTTGAGTTAGTCACCTCGGGGATTTTTTCCATTTTGCAGTAA AATGTTAAATTAATGTAGCCTGCCTCTATTTGTTGGGCAGGTAATTTCAAAGGGTTATTTGCCTCATCTC CTATCTTTAGTGAAATCTTATGTGTAATTATTCCACCGTGGGAACAGAGAATACCTGTTTAGTGTTGCAC TTTAGACTGGTGTCTGTTTTGTTAATGCAGCTGTGCCACAAATTCTCCTTTATCTTTTAAAAATGTTATA GCTTTAAATTTTGATTTATTTTGACTGTGGAATAAATACATGAATG ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCG |
Restriction Sites | SgfI-MluI |
OTI Disclaimer | Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs). |
Reference Data | |
RefSeq | NM_004718.2 |
Summary | Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein similar to polypeptides 1 and 2 of subunit VIIa in the C-terminal region, and also highly similar to the mouse Sig81 protein sequence. This gene is expressed in all tissues, and upregulated in a breast cancer cell line after estrogen treatment. It is possible that this gene represents a regulatory subunit of COX and mediates the higher level of energy production in target cells by estrogen. Several transcript variants, some protein-coding and others non-protein coding, have been found for this gene. [provided by RefSeq, Jan 2016] |
Locus ID | 9167 |
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