Dynamin 2 (DNM2) (NM_001005360) Human 3' UTR Clone

CAT#: SC210507

3`UTR clone of dynamin 2 (DNM2) transcript variant 1 for miRNA target validation

Specifications

Product Data

• Vector: pMirTarget
• Species: Human
• Transfection Reporter: RFP
• Assay Reporter: Luciferase
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Symbol: DNM2
• Synonyms: CMT2M; CMTDI1; CMTDIB; DI-CMTB; DYN2; DYNII; LCCS5
• ACCN: NM_001005360
• Insert Size: 897 bp
• Sequence Data:
  Insert Sequence

  >SC210507 3'UTR clone of NM_001005360
  The sequence shown below is from the reference sequence of NM_001005360. The complete sequence of this clone may contain minor differences, such as SNPs. Red=Cloning site Blue=Stop Codon
  
  
  CAATTGGCAGAGCTCAGAATTCAAGCGATCGC
  
  CCCACCATTATCCGCCCAGCCGAGCCATCCCTGCTCGACTAGGCCTCGAGGGGGGCGTGCTCTCGGGGGG
  GCCTCACGCACCCGCGGCGCAGGAGCTTCAGTGGTCTGGGGCCCTCCGCCGCCCCTATGCTGGGACCAGG
  CTCCCAGTGGGCAGCCCTGGCCTCTTCCTTAACGCTGGCCCCGGTCCAGGGCCGGCCCCTGTGCCTGGCT
  GGACACCGCACTGCGCAAAGGGGCCCTGGAGCTCCAGGCAGGGGGCGCTGGGGTGTTGCACTTTGGGGGA
  TGGAGTCTCAGGGTGGCAGAGGGGGGACCAGAACCCTTGACACCATCCTGAATGAGGGGTCCAGCCTGGG
  GGGGACTCTACCAAGGTCTTCTTGGGCTGGGAAAGCCCATGTAGGGCAGGCCTTCTATAAGTGCGGGCAC
  CAAGGGCGCCTACATCCCCAGGCCTTGCTGGGGTGCAGGGGTATATCAACTTCCCATTAGCAGGAGCTCC
  CCAGCGGCAAGCCTGGCCCAGTGGGCTCGGTAGTGCCCAGCTGGCAGGCCTGAGGTGTACATAGTCCTTC
  CCGGCCATATTAACCACACAGCCTGAGCCTGGCCCAGCCTCGGCTGCCAGAGGTGCCTTTGCTAGGCCCG
  GAGCCGTTGGCCCGGGCCGGCCTTGCCCTATTCCTCTCCTCCTCCTCCTCCTGGGTCCCCCAGGGTGGCT
  GGGCTTGGGCTATGTGGGTGGTGGTGGCGGGGGGTCTTGGGGGCCTCTCAGCTCCCGCCCATGCCTCCCT
  GATGGGTGGGCCCAGGGCGGCCTCTCTCTGAGGAGACCTCACCCACTCCTCGCTCAGTTTGACCACTGTA
  AGTGCCTGCACTCTGTATTCTATTAATAAACTAAAATAAAGGGAAGACGCTGCTGGT
  
  ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCG
• Restriction Sites: SgfI-MluI
• OTI Disclaimer: Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as 10 ug dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials.

Reference Data

• RefSeq: NM_001005360.1
• Summary: 'Dynamins represent one of the subfamilies of GTP-binding proteins. These proteins share considerable sequence similarity over the N-terminal portion of the molecule, which contains the GTPase domain. Dynamins are associated with microtubules. They have been implicated in cell processes such as endocytosis and cell motility, and in alterations of the membrane that accompany certain activities such as bone resorption by osteoclasts. Dynamins bind many proteins that bind actin and other cytoskeletal proteins. Dynamins can also self-assemble, a process that stimulates GTPase activity. Five alternatively spliced transcripts encoding different proteins have been described. Additional alternatively spliced transcripts may exist, but their full-length nature has not been determined. [provided by RefSeq, Jun 2010]'
• Locus ID: 1785