DMP1 (NM_001079911) Human 3' UTR Clone

CAT#: SC212052

3`UTR clone of dentin matrix acidic phosphoprotein 1 (DMP1) transcript variant 2 for miRNA target validation

Specifications

Product Data

• Vector: pMirTarget
• Species: Human
• Transfection Reporter: RFP
• Assay Reporter: Luciferase
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Symbol: DMP1
• Synonyms: ARHP; ARHR; DMP-1
• ACCN: NM_001079911
• Insert Size: 1037
• Sequence Data:
  Insert Sequence

  >SC212052 3'UTR clone of NM_001079911
  The sequence shown below is from the reference sequence of NM_001079911. The complete sequence of this clone may contain minor differences, such as SNPs. Red=Cloning site Blue=Stop Codon
  
  
  CAATTGGCAGAGCTCAGAATTCAAGCGATCGC
  
  AATGACTGCCAAGACGGCTATTAGCATCAGCTGTCCTAAGAAGCAGTTGTCACATAAAGGAGTCTTAGGG
  ACTTGAAAATGTATCATGATAACTATAATTTATTGATGTTTTGATCAAAAGAATAACCAGATGCCATATT
  TTTCCTGAAAGGAATTGCTGGACATTACACTTGTTTTTAGGGTGTCATCATTTCACAGAGGTTTAAATAC
  TGTGGAGTGACACCAGAACACAGCCAAAGAGGCTAGAAGCAAGAAAGGATCTGCATGATAACTTTGCAGC
  TGAGATAGTTCCTAATTCATCAACGTAACAAACAAAGCTATTGGGTGTCCATGATATACCAGGCACTATG
  CTAGGTGTTGAGAATGTAAAGCAGGTTAAGACTTGTTTCTTGCTCCTGAGGAGCGTATAGAAGGACCCAC
  AAAGCTACAGAGTTAAAGAGGGATATGTATAAGAGAAACAAGAATTGTTACAACCCAGTATGGTGAGTGC
  CAAGACAGAGAGCTATGAACACGATATCTATCTGGGAACACTGAGAAGGGTGACCAATGCGTTGGAGAAC
  GAGGGAGGGCTTCATAGCAGAAGACATTGGAGTTGGAAGGTTGCATAGGGTTTCCTCATTGGAGACCGGG
  AAATTCTATTCTTGGGATAAATAATAGTAAATTCTATAGGATTCAATACTTAGTTTGCAAAAGCACTTTG
  AAATTATGGCACAGTGAGTTGTTTTGGATAAGAAAATCTTTTTCTCCCAATTAATTTACCAATTCATCAT
  TTTTTTTTTTTTGTAGAACTCCCATAAACATCACCTTACTAATCACTGGTGATGATAAGAAGGATTGGGT
  CAGGAAGAGTGGGAGAAAGAAATTCCTCTTTACGTAGATACTTTTTAGCTTTATTTTTTCTAAAATCAGT
  TTGCGTGCAATGCTAGAAAAAAACTGTTCTCTGAGTCCTTTACAGAGCAAAATTCTGTATGTAAGATTCA
  ATTGATTTTTGACAAATACCATTTGAAATATTACCTCAACATAAAATACTTGTTTTG
  
  ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCG
• Restriction Sites: SgfI-MluI
• OTI Disclaimer: Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).

Reference Data

• RefSeq: NM_001079911.2
• Summary: Dentin matrix acidic phosphoprotein is an extracellular matrix protein and a member of the small integrin binding ligand N-linked glycoprotein family. This protein, which is critical for proper mineralization of bone and dentin, is present in diverse cells of bone and tooth tissues. The protein contains a large number of acidic domains, multiple phosphorylation sites, a functional arg-gly-asp cell attachment sequence, and a DNA binding domain. In undifferentiated osteoblasts it is primarily a nuclear protein that regulates the expression of osteoblast-specific genes. During osteoblast maturation the protein becomes phosphorylated and is exported to the extracellular matrix, where it orchestrates mineralized matrix formation. Mutations in the gene are known to cause autosomal recessive hypophosphatemia, a disease that manifests as rickets and osteomalacia. The gene structure is conserved in mammals. Two transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
• Locus ID: 1758