CHRFAM7A (NM_139320) Human 3' UTR Clone

CAT#: SC212097

3`UTR clone of CHRNA7 (cholinergic receptor nicotinic alpha 7 exons 5-10) and FAM7A (family with sequence similarity 7A exons A-E) fusion (CHRFAM7A) transcript variant 1

Specifications

Product Data

• Vector: pMirTarget
• Species: Human
• Transfection Reporter: RFP
• Assay Reporter: Luciferase
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Symbol: CHRFAM7A
• Synonyms: CHRNA7; CHRNA7-DR1; D-10; NACHRA7
• ACCN: NM_139320
• Insert Size: 1048
• Sequence Data:
  Insert Sequence

  >SC212097 3'UTR clone of NM_139320
  The sequence shown below is from the reference sequence of NM_139320. The complete sequence of this clone may contain minor differences, such as SNPs. Red=Cloning site Blue=Stop Codon
  
  
  CAATTGGCAGAGCTCAGAATTCAAGCGATCGC
  
  CCGTGTCCAAAGACTTTGCGTAACCACGCCTGGTTCTGTACATGTGGAAAACTCACAGATGGGCAAGGCC
  TTTGGCTTGGCGAGATTTGGGGGTGCTAATCCAGGACAGCATTACACGCCACAACTCCAGTGTTCCCTTC
  TGGCTGTCAGTCGTGTTGCTTACGGTTTCTTTGTTACTTTAGGTAGTAGAATCTCAGCACTTTGTTTCAT
  ATTCTCAGATGGGCTGATAGATATCCTTGGCACATCCGTACCATCGGTCAGCAGGGCCACTGAGTAGTCA
  TTTTGCCCATTAGCCCACTGCCTGGAAAGCCCTTCGGAGAGCTCCCCATGGCTCCTCACCACCGAGACAG
  TTGGTTTTGCATGTCTGCATGAAGGTCTACCTGAAAATTCAACATTTGCTTTTTGCTTGTGTACAAACCC
  AGATTGAAGCTAAAATAAACCAGACTCACTAAATCCTTTCCAATAATTGACTGGTGGAAGGAAAACAAAA
  AACAAAAACTAAAAACCTCTTAGCTTTTCTGCAATTCAACTTTTTATTTTTATTTTTATTTCTATCAAAG
  ACGGTAGAGAGAAACAGCTTGATGCTGTTTCTACATCAAAAAAAAAAAAAAAAAAGACAGACTGTTGGTC
  TTACTAAGGATGTTTTTACCAGCCTGCCTGACTTCTGCAAACCTACCCTGTCAAGGAGATCAAAGGGACG
  CAGGTTTCTGTTTATTCTGAACAAGGGCCAGGCCCCGCGGAGTGTCTTTGGTGGATCCCAGATAACTCCT
  AGGTGCTGCTCTCAGACACTGAGGAGTTGAGCAAATCTGTTCTATTCTGCAGAACCCATAGGACAAATAA
  GAGTTCTACTAGAATTAACAGCCCAAAAGAATAGCTACAGCTAAGTGAAGCCACTTACGTGGGCTTTAAA
  AAAATAATGTGTTAGCTGATTCACATGCACTGGAGTTAATTAGTCTTAGAAATGTGTGCATCCATACAAA
  TGCACAACATAAAGTGAACATATTCCTAGGCCCTTTCTGCCTGTGTCAGGGCCAGGAAGTAGAGGCTG
  
  ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCG
• Restriction Sites: SgfI-MluI
• OTI Disclaimer: Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).

Reference Data

• RefSeq: NM_139320.1
• Summary: The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The family member CHRNA7, which is located on chromosome 15 in a region associated with several neuropsychiatric disorders, is partially duplicated and forms a hybrid with a novel gene from the family with sequence similarity 7 (FAM7A). Alternative splicing has been observed, and two variants exist, for this hybrid gene. The N-terminally truncated products predicted by the largest open reading frames for each variant would lack the majority of the neurotransmitter-gated ion-channel ligand binding domain but retain the transmembrane region that forms the ion channel. Although current evidence supports transcription of this hybrid gene, translation of the nicotinic acetylcholine receptor-like protein-encoding open reading frames has not been confirmed. [provided by RefSeq, Jul 2008]
• Locus ID: 89832