Hyaluronan synthase 2 (HAS2) (NM_005328) Human 3' UTR Clone
CAT#: SC212271
3`UTR clone of hyaluronan synthase 2 (HAS2) for miRNA target validation
Product Images
![](https://cdn.origene.com/img/defaults-img.jpg)
Other products for "HAS2"
Specifications
Product Data | |
Vector | pMirTarget |
Species | Human |
Transfection Reporter | RFP |
Assay Reporter | Luciferase |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Symbol | HAS2 |
Synonyms | MGC126241; MGC126242 |
ACCN | NM_005328 |
Insert Size | 1123 bp |
Sequence Data |
>SC212271 3'UTR clone of NM_005328
The sequence shown below is from the reference sequence of NM_005328. The complete sequence of this clone may contain minor differences, such as SNPs. Red=Cloning site Blue=Stop Codon CAATTGGCAGAGCTCAGAATTCAAGCGATCGC AGGCGGAAGAAGGGACAACAATATGACATGGTGCTTGATGTATGATCTTCCATGTTTTGACGTTTGCAGT CACACACAACACCTTAGTTCCTCTAGGGGCTGTACAGTATTGTGGCATCAGATAATGCCACCAAAGGAGA CATATCACTGCTGCTGGGACTTGAACAAAGACATTTATATGGGTTTATTTTCATTCTGCCAAAGTAAAAC AATACATCAACAAGAAGAAACTCAGATTTAACCTGTTATTTCTATGAAAATGGGATGAATTCTTTGTTTA TGCACTTTTTCCTTACTGTGCATCCGCCTGAAAGTGTTTTGCCCTATATACCTCACTAGCCATGCTTTAT GTGGGTTATCATGGAAGAAAAGGATTTTGGAAACTCAAGGAAAAGTTCTTTCAACCTATACAACCTAACT TATGGACTGTTTTGATAGATGATAATTTTTTTTTTTTAGGAAGGATTTTCTTTTTAACTTTACCAAATGA AATGCCAAAGGAAGTTTTAAAGGCCGTTGGCTGTGCTGTATTTTGATATAATTGTACTGTGTTTTTAAAT TTTGTATGCCAATCTTAAAGACAAATTTTGCATATTCTCTATTTTACTTTTCTGCCAAAATAAACCTGTT CTTCCTTTTTTAAAATAAAATAAGTTCTTAAAAAATTTATACTTAAAAAATCCTGCCCAAAATGTGAAGC TTGGTTGACTGATGTTCATGATAGAAAGAATAAAATGTTTCTCTCTCTCTACCTTTTAAAATTGAATAGT TTATTTCTGTGAAAGAAGTATTTAAACTTTCAATATTTTAACTTTTTGTTTTTATTTCTTTTAGAAAAGG CCAATATACCTATCACACTTTGGAAGTAAAAATACACACTTTCGTGTGTACCTAAAAAAAAAATCGTTGA AAATCAAGGCCAAAGGTAGTGCAATTTTTTCATTAAGATTTAAAAAAAAGGGAATGATAGTCTTTGAAAG AAAACAGTAGGCATCCAGCACTGGACAAAACATGGGTATCAAAGATGAATAATCTTTGGAGATTCTGGCA GTGTTTTCCCAGAACAAGTCAAGTGGAAAGTGGAGAAATTATCTGTATAATTTTGGACACATACAATGCA GTT ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCG |
Restriction Sites | SgfI-MluI |
OTI Disclaimer | Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs). |
Product Components | The cDNA clone is shipped in a 2-D bar-coded Matrix tube as 10 ug dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. |
Reference Data | |
RefSeq | NM_005328.2 |
Summary | ' Hyaluronan or hyaluronic acid (HA) is a high molecular weight unbranched polysaccharide synthesized by a wide variety of organisms from bacteria to mammals, and is a constituent of the extracellular matrix. It consists of alternating glucuronic acid and N-acetylglucosamine residues that are linked by beta-1-3 and beta-1-4 glycosidic bonds. HA is synthesized by membrane-bound synthase at the inner surface of the plasma membrane, and the chains are extruded through pore-like structures into the extracellular space. It serves a variety of functions, including space filling, lubrication of joints, and provision of a matrix through which cells can migrate. HA is actively produced during wound healing and tissue repair to provide a framework for ingrowth of blood vessels and fibroblasts. Changes in the serum concentration of HA are associated with inflammatory and degenerative arthropathies such as rheumatoid arthritis. In addition, the interaction of HA with the leukocyte receptor CD44 is important in tissue-specific homing by leukocytes, and overexpression of HA receptors has been correlated with tumor metastasis. HAS2 is a member of the newly identified vertebrate gene family encoding putative hyaluronan synthases, and its amino acid sequence shows significant homology to glycosaminoglycan synthetase (DG42) from Xenopus laevis, and human and murine hyaluronan synthase 1. [provided by RefSeq, Jul 2008]' |
Locus ID | 3037 |
Documents
Product Manuals |
FAQs |
Resources
{0} Product Review(s)
0 Product Review(s)
Submit review
Be the first one to submit a review
Product Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.