Nav1.6 (SCN8A) (NM_014191) Human 3' UTR Clone

CAT#: SC212371

3`UTR clone of sodium channel voltage gated type VIII alpha subunit (SCN8A) for miRNA target validation

Specifications

Product Data

• Vector: pMirTarget
• Species: Human
• Transfection Reporter: RFP
• Assay Reporter: Luciferase
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Symbol: SCN8A
• Synonyms: BFIS5; CERIII; CIAT; EIEE13; MED; MYOCL2; NaCh6; Nav1.6; PN4
• ACCN: NM_014191
• Insert Size: 1102 bp
• Sequence Data:
  Insert Sequence

  >SC212371 3'UTR clone of NM_014191
  The sequence shown below is from the reference sequence of NM_014191. The complete sequence of this clone may contain minor differences, such as SNPs. Red=Cloning site Blue=Stop Codon
  
  
  CAATTGGCAGAGCTCAGAATTCAAGCGATCGC
  
  GAGGTCAGAGAATCCAAGTGTTAGAGGAGAACAAAAATTCAGTATTATACAGATCTAAAACTCGCAAGTG
  AAAGATTGTTTACAAACTTCCTGAATATTATCAATGCAGAACAGCTGTGGAGACTCTAACCTGAAGATCT
  ATACCAAACGTCGTCTGCTTACCACGTAACACAGCTGCATCTTGAGCAGTGACCTGCCAAGGGCAAAGGA
  CCCCGCTCCCTAGACTTACAGATTTTCTAATGCTTGGGCAGGTGGTTACTGCATGTTCCACATCAGTCAA
  TGCAACTTAGGACAAAACTAACCAGATACAGAAACAGAAGAGAGGCTGCCGGGACCAGCATATTTCCGTT
  GCAGCCAAATGGATTTTATTTTTTCATTTTATTGATTCTCAGAAGCAGAAAGCATCACTTTAAAAGTTCG
  TTTGTTCATGCAAACTATATTTGCATTCTTACATTAGTTAAGCTAAGCAGCAAAAAGAAAACACACACAC
  ACACTCACATTTAGCCCATGTCATTTAATTGTCAGTTTCTTTGACATAAAGCGCATCTTCTCCACATGGG
  CTTCACGTGGTTTGGAGATGGGTGGGGGAAAACAATCAGGTTTCTTCAGGCTGAGGAGGACTTGCTCAGG
  CCGATTCCAAACATTGTGCTCGTTCAATGCGTAGAAATGATTTGCATGATGGCATGCCGTGATCAGAAGT
  CATGCATGAGATCCATACACCACAGGACACTACTAATCTAGTCCCTTGCACTGGGTCAGCCTTTGGACAG
  GACCCAGCCCTGCACCGTTCACTGTATTTGGAGAAAATGGTAAGAGTTCCATACCGGCTACAATTCTTTG
  AGTTCTTAAAAGTCCTTCATACACCTTCTGGGTAGGGAAACAACCAACTAATTGACTAACACCACCAACA
  ACAAAAAACAAACCCAATCCAACAAGCAGATGGATCCGTTGCGTGTATATGTTTAACAGACATCTCTAAC
  ATACAGCCATTGTTGCACATTTTGCAAGATGAACTATTTAATGCTGCTCTGTGTCCAGTACATGGGGGAG
  ACTTTGATCCCAAATGGCTTGTACTATTTATGTCACTGTAAAACCAAATCCT
  
  ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCG
• Restriction Sites: SgfI-MluI
• OTI Disclaimer: Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as 10 ug dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials.

Reference Data

• RefSeq: NM_014191.2
• Summary: 'This gene encodes a member of the sodium channel alpha subunit gene family. The encoded protein forms the ion pore region of the voltage-gated sodium channel. This protein is essential for the rapid membrane depolarization that occurs during the formation of the action potential in excitable neurons. Mutations in this gene are associated with cognitive disability, pancerebellar atrophy and ataxia. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2010]'
• Locus ID: 6334