OTUD5 (NM_017602) Human 3' UTR Clone

CAT#: SC212869

3`UTR clone of OTU domain containing 5 (OTUD5) transcript variant 1 for miRNA target validation

Specifications

Product Data

• Vector: pMirTarget
• Species: Human
• Transfection Reporter: RFP
• Assay Reporter: Luciferase
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Symbol: OTUD5
• Synonyms: DUBA
• ACCN: NM_017602
• Insert Size: 1182
• Sequence Data:
  Insert Sequence

  >SC212869 3'UTR clone of NM_017602
  The sequence shown below is from the reference sequence of NM_017602. The complete sequence of this clone may contain minor differences, such as SNPs. Red=Cloning site Blue=Stop Codon
  
  
  CAATTGGCAGAGCTCAGAATTCAAGCGATCGC
  
  CAAAGTGCACAGAGACCCGCCCCCAGACAAGAGTTGATGGAGACCCAGGGATTGGACACCATCTCCCAAC
  CCCAGTACTCCTGCTCTCCGGTGCCACCTCACCTTCTTTGGCTTCTTCCCTCTTGCCTCCTTCTGTTCTT
  TCTGCTCTCCCCTCTTTTCCCTCCTCCTCACTTCCCTCTGGCTAGCCCACCCCTGCACTCTCTCTCATTG
  CCGCTGCCACTATCACCTGTCTCTCTGCCAGCTGATGTGCCCTGTTGCCCCCCACCCCATCCCGCACAGA
  ACCATCCCTGCATTCCACAGGGGACTCGGGCAAGGGTGCCGAAGATAGACAAGAGGCACACAGAGACAGA
  CCAACTGGCAGCCAGGCAGCCCCAGAGGAGAGAGACATTCAGACAGAGGAAAGTCTCCCTGCCCCTCATT
  CCTTCCAAGATGAGAAAAACTTGCCGCCACCCCCCGACACTGATGCCAGGGAGGTGGGAGGAAGAAGTGG
  GAAATTTCCCTTCCCAGTACCCCCAAGAACGTCTGAGCCTTCAATGTTGAATTTTTTCTTTATTAAAATT
  ACTTTTATCTTATAAAATCAACTAATCAAAAATGATATAGACGACAGCACTGGCTCTGTGAAGGTGGCAT
  CTTTCTGGGCAGGCAGGCCATGGGGCATGGAGGAGGGTGCAAAGATATGGGTTGCTGTCTTCTGGCCTCC
  AGCTGCATGGAGGCCGGCCCAGGGTCTAGGGTGTGCACTGGGCAAGGGCAGGGCGGCAGGTGTCAGGCCG
  GCTTGGACAATGAAACCCTGACCTTGCTGCATTCCTTTTGCTTCCACCACCACTAGCTTCTTTGGAATCT
  TGGGGTGGGGGTCATCTTTGGGGATTATGGCTGCCACCCGGGATTTGAGTGTAGGGAGTGTGGGAGCAGC
  CTTGGCAGATGGGGCACCCGTGCCCTGCAGGTGTTGACAAGATCCGCCATCTGTAATGTCCTTGGCACAA
  TAAAACCAAATGTCAGTTTCCCTGAGCGACTCTGTTCTGTGTGGGGCAGGGGTTGGGCGGGCCTCTGGGC
  AGAGGATGCAATGGCACGGACCTTGGCTTGACCTCAGAGGTGTGAATGCTCTCCAGCAGGGTCTGTCTGG
  GGGCCTGGAGTTTGTATTTGATTTGCTGCTTATTAAACCTCCTTCTGGACCTATTGCCACTG
  
  ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCG
• Restriction Sites: SgfI-MluI
• OTI Disclaimer: Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).

Reference Data

• RefSeq: NM_017602.3
• Summary: This gene encodes a member of the OTU (ovarian tumor) domain-containing cysteine protease superfamily. The OTU domain confers deubiquitinase activity and the encoded protein has been shown to suppress the type I interferon-dependent innate immune response by cleaving the polyubiquitin chain from an essential type I interferon adaptor protein. Cleavage results in disassociation of the adaptor protein from a downstream signaling complex and disruption of the type I interferon signaling cascade. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Oct 2008]
• Locus ID: 55593