DPYD (NM_000110) Human 3' UTR Clone
CAT#: SC213408
3`UTR clone of dihydropyrimidine dehydrogenase (DPYD) transcript variant 1 for miRNA target validation
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Specifications
Product Data | |
Vector | pMirTarget |
Species | Human |
Transfection Reporter | RFP |
Assay Reporter | Luciferase |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Symbol | DPYD |
Synonyms | DHP; DHPDHASE; DPD |
ACCN | NM_000110 |
Insert Size | 1249 bp |
Sequence Data |
>SC213408 3'UTR clone of NM_000110
The sequence shown below is from the reference sequence of NM_000110. The complete sequence of this clone may contain minor differences, such as SNPs. Red=Cloning site Blue=Stop Codon CAATTGGCAGAGCTCAGAATTCAAGCGATCGC GAACCAAAGAGAGGCGTACCCTTATCTGTGAATCCGGTGTGTTAAGGTGATTTGTGAAACAGTTGCTGTG AACTTTCATGTCACCTACATATGCTGATCTTTTAAAATCATGATCCTTGTGTTCAGCTCTTTCCAAATTA AAACAAATATACATTTTCTAAATAAAAATATGTAATTTCAAAATACATTTGTAAGTGTAAAAAATGTCTC ATGTCAATGACCATTCAATTAGTGGTCATAAAATAGAATAATTCTTTTCTGAGGATAGTAGTTAAATAAC TGTGTGGCAGTTAATTGGATGTTCACTGCCAGTTGTCTTATGTGAAAAATTAACTTTTTTGTGGCAATTA GTGTGACAGTTTCCAAATTGCCCTATGCTGTGCTCCATATTTGATTTCTAATTGTAAGTGAAATTAAGCA TTTTGAAACAAAGTACTCTTTAACATACAAGAAAATGTATCCAAGGAAACATTTTATCATTAAAAATTAC CTTTAATTTTAATGCTGTTTCTAAGAAAATGTAGTTAGCTCCATAAAGTACAAATGAAGAAAGTCAAAAA ATTATTTGCTATGGCAGGATAAGAAAGCCTAAAATTGAGTTTGTAGAACTTTATTAAGTAAAATCCCCTT CGCTGAAATTGCTTATTTTTGGTGTTGGATAGAGGATAGGGAGAATATTTACTAACTAAATACCATTCAC TACTCATGCGTGAGATGGGTGTACAAACTCATCCTCTTTTAATGGCATTTCTCTTTAAACTATGTTCCTA ACAAAATGAGATGATAGGATAGATCCTGGTTACCACTCTTTTGCTGTGCACATACGGGCTCTGACTGGTT TTAATAGTCACCTTCATGATTATAGCAACTAATGTTTGAACAAAGCTCAAAGTATGCAATGCTTCATTAT TCAAGAATGAAAAATATAATGTTGATAATATATATTAAGTGTGCCAAATCAGTTTGACTACTCTCTGTTT TAGTGTTTATGTTTAAAAGAAATATATTTTTTGTTATTATTAGATAATATTTTTGTATTTCTCTATTTTC ATAATCAGTAAATAGTGTCATATAAACTCATTTATCTCCTCTTCATGGCATCTTCAATATGAATCTATAA GTAGTAAATCAGAAAGTAACAATCTATGGCTTATTTCTATGACAAATTCAAGAGCTAGAAAAATAAAATG TTTCATTATGCACTTTTAGAAATGCATATTTGCCACAAAACCTGTATTACTGAATAATA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCG |
Restriction Sites | SgfI-MluI |
OTI Disclaimer | Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs). |
Product Components | The cDNA clone is shipped in a 2-D bar-coded Matrix tube as 10 ug dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. |
Reference Data | |
RefSeq | NM_000110.3 |
Summary | 'The protein encoded by this gene is a pyrimidine catabolic enzyme and the initial and rate-limiting factor in the pathway of uracil and thymidine catabolism. Mutations in this gene result in dihydropyrimidine dehydrogenase deficiency, an error in pyrimidine metabolism associated with thymine-uraciluria and an increased risk of toxicity in cancer patients receiving 5-fluorouracil chemotherapy. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]' |
Locus ID | 1806 |
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