P2X1 (P2RX1) (NM_002558) Human 3' UTR Clone

CAT#: SC213589

3`UTR clone of purinergic receptor P2X ligand-gated ion channel 1 (P2RX1) for miRNA target validation

Specifications

Product Data

• Vector: pMirTarget
• Species: Human
• Transfection Reporter: RFP
• Assay Reporter: Luciferase
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Symbol: P2RX1
• Synonyms: P2X1
• ACCN: NM_002558
• Insert Size: 1226
• Sequence Data:
  Insert Sequence

  >SC213589 3'UTR clone of NM_002558
  The sequence shown below is from the reference sequence of NM_002558. The complete sequence of this clone may contain minor differences, such as SNPs. Red=Cloning site Blue=Stop Codon
  
  
  CAATTGGCAGAGCTCAGAATTCAAGCGATCGC
  
  TGCAGGAGAACATGAGGACATCCTGATGCTCGGGCCCCAACTCCTGACTGGGTGCAGCGTGAGGCTTCAG
  CCTGGAGCCCTGGTGGGTCCCAGCCAGGGCAGAGGGGCCTCCCCAGGAAGTCTCCTACCCTCTCAGCCAG
  GCAGAGAGCAGTTTGCCAGAAGCTCAGGGTGCATAGTAGGAGAGACCTGTGCAAATCTGAGCTCCGGCTC
  CGACCCCACACACCCTGAGGGAGCCCTACCCTAGCCTCAGCCGCTCCTGGTGGGGAATGGCTGGGGCTGG
  GCAGGACCCTCCCACACACCTGCACCCTAGCTTCGTGCTTCTCTCTCCGGACTCTCATTATCCAACCCGC
  TGCCTCCATTTCTCTAGATCTGTGCTCTCCGATGTGGCAGTCAGTAACCATAGGTGACTAAATTAAACTA
  AAATAAAATAGAATGAAACACAAAATTCAATTCCTCGGCTGAACTAGCCACATTTCAACTGCTCAGTAGA
  TACGTGTGGTTAGTGGCTGCCATACTGGACAGCTCGGGGCATTTTCACTGTCAAAGAAAGTTCTATTAGA
  CAGCCCTGCTTGAGCCCTGTTTCTTCCTGGCCTTCGGTTTCCCTGGGGAACTTATCGACAATGCAAGCTC
  CTGGGCCCACCCCCAGACCTCCTGAACCAAAAGCTCCAGGGCTGGCCGTATGATCTGTGTGGATGGCAAA
  CTCCCCAGGCCATTCTGGGACCTAAGTTTAAGAAGTGCCGTCCTCGAACTTTCTGACTCTAAGCTCCTGA
  GCGGGAGTCAGACTTAGCCCTGAGCCTGCACTTCCTGTTCAGGTGCAGACACTGAACAGGGTCTCAAACA
  CCTTCAGCATGTGTGTTGTGTGCTCACGTGCCACACAGTGTCTCATGCACACAACCCAGTGTACACACCA
  CCTACGTGCACACAGCATCCTTCCACACTGTGTATGTGAACAGCTTGGGCCCTGCAAACACAACCATCTA
  CACACATCTACACCCCCAAGCACACACACATGGTCCGTGCCATGTCACCTCCATAGGGAAAGGCTTCTCT
  CCAAGTGTGCCAGGCCAGGACAGCCCTCCCAGCCATGAATCCTTACTCAGCTACCTCGGGTTGGGGTGGG
  AGCCCCAGCCAAATCCTGGGCTCCCTGCCTGTGGCTCAGCCCCAGCTCCCAAGGCCTGCCTGGCTCTGTC
  TGAACAGAAGGTCTGGGGGAAGCGACGGGTGGAGTA
  
  ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCG
• Restriction Sites: SgfI-MluI
• OTI Disclaimer: Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).

Reference Data

• RefSeq: NM_002558.2
• Summary: The protein encoded by this gene belongs to the P2X family of G-protein-coupled receptors. These proteins can form homo-and heterotimers and function as ATP-gated ion channels and mediate rapid and selective permeability to cations. This protein is primarily localized to smooth muscle where binds ATP and mediates synaptic transmission between neurons and from neurons to smooth muscle and may being responsible for sympathetic vasoconstriction in small arteries, arterioles and vas deferens. Mouse studies suggest that this receptor is essential for normal male reproductive function. This protein may also be involved in promoting apoptosis. [provided by RefSeq, Jun 2013]
• Locus ID: 5023