P2RX7 (NM_002562) Human 3' UTR Clone

CAT#: SC213607

3`UTR clone of purinergic receptor P2X ligand-gated ion channel 7 (P2RX7) for miRNA target validation

Specifications

Product Data

• Vector: pMirTarget
• Species: Human
• Transfection Reporter: RFP
• Assay Reporter: Luciferase
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Symbol: P2RX7
• Synonyms: P2X7
• ACCN: NM_002562
• Insert Size: 1276
• Sequence Data:
  Insert Sequence

  >SC213607 3'UTR clone of NM_002562
  The sequence shown below is from the reference sequence of NM_002562. The complete sequence of this clone may contain minor differences, such as SNPs. Red=Cloning site Blue=Stop Codon
  
  
  CAATTGGCAGAGCTCAGAATTCAAGCGATCGC
  
  ACAGTGGCTTCAAGAGTCCTTACTGAAGCCAGGCACCGTGGCTCACGTCTGTAATCCCAGCGCTTTGGGA
  GGCCGAGGCAGGCAGATCACCTGAGGTCGGGAGTTGGAGACCCGCCTGGCTAACAAGGCGAAATCCTGTC
  TGTACTAAAAATACAAAAATCAGCCAGACATGGTGGCATGCACCTGCAATCCCAGCTACTCGGGAGGCTG
  AGGCACAAGAATCACTTGAACCCGGGAGGCAGAGGTTGTAGTGAGCCCAGATTGTGCCACTGCTCTCCAG
  CCTGGGAGGCACAGCAAACTGTCCCCCAAAAAAAAAAAAGAGTCCTTACCAATAGCAGGGGCTGCAGTAG
  CCATGTTAACATGACATTTACCAGCAACTTGAACTTCACCTGCAAAGCTCTGTGGCCACATTTTCAGCCA
  AAGGGAAATATGCTTTCATCTTCTGTTGCTCTCTGTGTCTGAGAGCAAAGTGACCTGGTTAAACAAACCA
  GAATCCCTCTACATGGACTCAGAGAAAAGAGATTGAGATGTAAGTCTCAACTCTGTCCCCAGGAAGTTGT
  GTGACCCTAGGCCTCTCACCTCTGTGCCTCTGTCTCCTTGTTGCCCAACTACTATCTCAGAGATATTGTG
  AGGACAAATTGAGACAGTGCACATGAACTGTCTTTTAATGTGTAAAGATCTACATGAATGCAAAACATTT
  CATTATGAGGTCAGACTAGGATAATGTCCAACTAAAAACAAACCCTTTTCATCCTGGCTGGAGAATGTGG
  AGAACTAAAGGTGGCCACAAATTCTTTGACACTCAAGTCCCCCAAGACCTAAGGGTTTTATCTCCTCCCC
  TTGAATATGGGTGGCTCTGATTGCTTTATCCAAAAGTGGAAGTGACATTGTGTCAGTTTCAGATCCTGAT
  CTTAAGAGGCTGACAGCTTCTACTTGCTGTCCCTTGGAACTCTTGCTATCGGGGAAGCCAGACGCCATTT
  AAAAGTCTGCCTATCCTGGCCAGGTGTGGTGGCTCACACCTGTAATCCCAGCACTTTGGGAGACCAAGGC
  GGGCGGATCACTTAAAGTCAGGAGTCCAAGACCAGACTCGCCAACATGGTGAAACCGTATCTCTAATAAA
  AATACAAAAATTAGCTGGGCATGGTGCGGGCACCTGTAGTCCTAGCTATCAAGAGGCTGAGACAGGAGAA
  ACACTTGAACCTGGGAGGTGGAGGTTGCATTGAGCTGAGATCGTGCCACTGCACTCCAGGCTGGGTGACA
  GAGCGAGACTCCATCT
  
  ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCG
• Restriction Sites: SgfI-MluI
• OTI Disclaimer: Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).

Reference Data

• RefSeq: NM_002562.4
• Summary: The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression. Multiple alternatively spliced variants have been identified, most of which fit nonsense-mediated decay (NMD) criteria. [provided by RefSeq, Jul 2010]
• Locus ID: 5027