Frizzled 6 (FZD6) (NM_003506) Human 3' UTR Clone

CAT#: SC214183

3`UTR clone of frizzled homolog 6 (Drosophila) (FZD6) transcript variant 1 for miRNA target validation

Specifications

Product Data

• Vector: pMirTarget
• Species: Human
• Transfection Reporter: RFP
• Assay Reporter: Luciferase
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Symbol: FZD6
• Synonyms: FZ-6; FZ6; HFZ6; NDNC10
• ACCN: NM_003506
• Insert Size: 1377
• Sequence Data:
  Insert Sequence

  >SC214183 3'UTR clone of NM_003506
  The sequence shown below is from the reference sequence of NM_003506. The complete sequence of this clone may contain minor differences, such as SNPs. Red=Cloning site Blue=Stop Codon
  
  
  CAATTGGCAGAGCTCAGAATTCAAGCGATCGC
  
  GGAGTGAGAAAAGAGCAGGGAGGTGGTTGTCATTCAGATACTTGAAGAACATTTTCTCTCGTTACTCAGA
  AGCAAATTTGTGTTACACTGGAAGTGACCTATGCACTGTTTTGTAAGAATCACTGTTACATTCTTCTTTT
  GCACTTAAAGTTGCATTGCCTACTGTTATACTGGAAAAAATAGAGTTCAAGAATAATATGACTCATTTCA
  CACAAAGGTTAATGACAACAATATACCTGAAAACAGAAATGTGCAGGTTAATAATATTTTTTTAATAGTG
  TGGGAGGACAGAGTTAGAGGAATCTTCCTTTTCTATTTATGAAGATTCTACTCTTGGTAAGAGTATTTTA
  AGATGTACTATGCTATTTTACTTTTTTGATATAAAATCAAGATATTTCTTTGCTGAAGTATTTAAATCTT
  ATCCTTGTATCTTTTTATACATATTTGAAAATAAGCTTATATGTATTTGAACTTTTTTGAAATCCTATTC
  AAGTATTTTTATCATGCTATTGTGATATTTTAGCACTTTGGTAGCTTTTACACTGAATTTCTAAGAAAAT
  TGTAAAATAGTCTTCTTTTATACTGTAAAAAAAGATATACCAAAAAGTCTTATAATAGGAATTTAACTTT
  AAAAACCCACTTATTGATACCTTACCATCTAAAATGTGTGATTTTTATAGTCTCGTTTTAGGAATTTCAC
  AGATCTAAATTATGTAACTGAAATAAGGTGCTTACTCAAAGAGTGTCCACTATTGATTGTATTATGCTGC
  TCACTGATCCTTCTGCATATTTAAAATAAAATGTCCTAAAGGGTTAGTAGACAAAATGTTAGTCTTTTGT
  ATATTAGGCCAAGTGCAATTGACTTCCCTTTTTTAATGTTTCATGACCACCCATTGATTGTATTATAACC
  ACTTACAGTTGCTTATATTTTTTGTTTTAACTTTTGTTTTTTAACATTTAGAATATTACATTTTGTATTA
  TACAGTACCTTTCTCAGACATTTTGTAGAATTCATTTCGGCAGCTCACTAGGATTTTGCTGAACATTAAA
  AAGTGTGATAGCGATATTAGTGCCAATCAAATGGAAAAAAGGTAGTTTTAATAAACAAGACACAACGTTT
  TTATACAACATACTTTAAAATATTAAGGAGTTTTCTTAATTTTGTTTCCTATTAAGTATTATTCTTTGGG
  CAAGATTTTCTGATGCTTTTGATTTTCTCTCAATTTAGCATTTGCTTTTGGTTTTTTTCTCTATTTAGCA
  TTCTGTTAAGGCACAAAAACTATGTACTGTATGGGAAATGTTGTAAATATTACCTTTTCCACATTTTAAA
  CAGACAACTTTGAATACAAAAACTTTGTTTTGTGTGATCTTTTCATT
  
  ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCG
• Restriction Sites: SgfI-MluI
• OTI Disclaimer: Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).

Reference Data

• RefSeq: NM_003506.3
• Summary: This gene represents a member of the 'frizzled' gene family, which encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The protein encoded by this family member contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, and seven transmembrane domains, but unlike other family members, this protein does not contain a C-terminal PDZ domain-binding motif. This protein functions as a negative regulator of the canonical Wnt/beta-catenin signaling cascade, thereby inhibiting the processes that trigger oncogenic transformation, cell proliferation, and inhibition of apoptosis. Alternative splicing results in multiple transcript variants, some of which do not encode a protein with a predicted signal peptide. [provided by RefSeq, Aug 2011]
• Locus ID: 8323