Frizzled 6 (FZD6) (NM_003506) Human 3' UTR Clone
CAT#: SC214183
3`UTR clone of frizzled homolog 6 (Drosophila) (FZD6) transcript variant 1 for miRNA target validation
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Specifications
Product Data | |
Vector | pMirTarget |
Species | Human |
Transfection Reporter | RFP |
Assay Reporter | Luciferase |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Symbol | FZD6 |
Synonyms | FZ-6; FZ6; HFZ6; NDNC10 |
ACCN | NM_003506 |
Insert Size | 1377 |
Sequence Data |
>SC214183 3'UTR clone of NM_003506
The sequence shown below is from the reference sequence of NM_003506. The complete sequence of this clone may contain minor differences, such as SNPs. Red=Cloning site Blue=Stop Codon CAATTGGCAGAGCTCAGAATTCAAGCGATCGC GGAGTGAGAAAAGAGCAGGGAGGTGGTTGTCATTCAGATACTTGAAGAACATTTTCTCTCGTTACTCAGA AGCAAATTTGTGTTACACTGGAAGTGACCTATGCACTGTTTTGTAAGAATCACTGTTACATTCTTCTTTT GCACTTAAAGTTGCATTGCCTACTGTTATACTGGAAAAAATAGAGTTCAAGAATAATATGACTCATTTCA CACAAAGGTTAATGACAACAATATACCTGAAAACAGAAATGTGCAGGTTAATAATATTTTTTTAATAGTG TGGGAGGACAGAGTTAGAGGAATCTTCCTTTTCTATTTATGAAGATTCTACTCTTGGTAAGAGTATTTTA AGATGTACTATGCTATTTTACTTTTTTGATATAAAATCAAGATATTTCTTTGCTGAAGTATTTAAATCTT ATCCTTGTATCTTTTTATACATATTTGAAAATAAGCTTATATGTATTTGAACTTTTTTGAAATCCTATTC AAGTATTTTTATCATGCTATTGTGATATTTTAGCACTTTGGTAGCTTTTACACTGAATTTCTAAGAAAAT TGTAAAATAGTCTTCTTTTATACTGTAAAAAAAGATATACCAAAAAGTCTTATAATAGGAATTTAACTTT AAAAACCCACTTATTGATACCTTACCATCTAAAATGTGTGATTTTTATAGTCTCGTTTTAGGAATTTCAC AGATCTAAATTATGTAACTGAAATAAGGTGCTTACTCAAAGAGTGTCCACTATTGATTGTATTATGCTGC TCACTGATCCTTCTGCATATTTAAAATAAAATGTCCTAAAGGGTTAGTAGACAAAATGTTAGTCTTTTGT ATATTAGGCCAAGTGCAATTGACTTCCCTTTTTTAATGTTTCATGACCACCCATTGATTGTATTATAACC ACTTACAGTTGCTTATATTTTTTGTTTTAACTTTTGTTTTTTAACATTTAGAATATTACATTTTGTATTA TACAGTACCTTTCTCAGACATTTTGTAGAATTCATTTCGGCAGCTCACTAGGATTTTGCTGAACATTAAA AAGTGTGATAGCGATATTAGTGCCAATCAAATGGAAAAAAGGTAGTTTTAATAAACAAGACACAACGTTT TTATACAACATACTTTAAAATATTAAGGAGTTTTCTTAATTTTGTTTCCTATTAAGTATTATTCTTTGGG CAAGATTTTCTGATGCTTTTGATTTTCTCTCAATTTAGCATTTGCTTTTGGTTTTTTTCTCTATTTAGCA TTCTGTTAAGGCACAAAAACTATGTACTGTATGGGAAATGTTGTAAATATTACCTTTTCCACATTTTAAA CAGACAACTTTGAATACAAAAACTTTGTTTTGTGTGATCTTTTCATT ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCG |
Restriction Sites | SgfI-MluI |
OTI Disclaimer | Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs). |
Reference Data | |
RefSeq | NM_003506.3 |
Summary | This gene represents a member of the 'frizzled' gene family, which encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The protein encoded by this family member contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, and seven transmembrane domains, but unlike other family members, this protein does not contain a C-terminal PDZ domain-binding motif. This protein functions as a negative regulator of the canonical Wnt/beta-catenin signaling cascade, thereby inhibiting the processes that trigger oncogenic transformation, cell proliferation, and inhibition of apoptosis. Alternative splicing results in multiple transcript variants, some of which do not encode a protein with a predicted signal peptide. [provided by RefSeq, Aug 2011] |
Locus ID | 8323 |
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