BMP6 (NM_001718) Human 3' UTR Clone

CAT#: SC214295

3`UTR clone of bone morphogenetic protein 6 (BMP6) for miRNA target validation

Specifications

Product Data

• Vector: pMirTarget
• Species: Human
• Transfection Reporter: RFP
• Assay Reporter: Luciferase
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Symbol: BMP6
• Synonyms: VGR; VGR1
• ACCN: NM_001718
• Insert Size: 1383 bp
• Sequence Data:
  Insert Sequence

  >SC214295 3'UTR clone of NM_001718
  The sequence shown below is from the reference sequence of NM_001718. The complete sequence of this clone may contain minor differences, such as SNPs. Red=Cloning site Blue=Stop Codon
  
  
  CAATTGGCAGAGCTCAGAATTCAAGCGATCGC
  
  AGAGCTTGTGGATGCCACTAACTCGAAACCAGATGCTGGGGACACACATTCTGCCTTGGATTCCTAGATT
  ACATCTGCCTTAAAAAAACACGGAAGCACAGTTGGAGGTGGGACGATGAGACTTTGAAACTATCTCATGC
  CAGTGCCTTATTACCCAGGAAGATTTTAAAGGACCTCATTAATAATTTGCTCACTTGGTAAATGACGTGA
  GTAGTTGTTGGTCTGTAGCAAGCTGAGTTTGGATGTCTGTAGCATAAGGTCTGGTAACTGCAGAAACATA
  ACCGTGAAGCTCTTCCTACCCTCCTCCCCCAAAAACCCACCAAAATTAGTTTTAGCTGTAGATCAAGCTA
  TTTGGGGTGTTTGTTAGTAAATAGGGAAAATAATCTCAAAGGAGTTAAATGTATTCTTGGCTAAAGGATC
  AGCTGGTTCAGTACTGTCTATCAAAGGTAGATTTTACAGAGAACAGAAATCGGGGAAGTGGGGGGAACGC
  CTCTGTTCAGTTCATTCCCAGAAGTCCACAGGACGCACAGCCCAGGCCACAGCCAGGGCTCCACGGGGCG
  CCCTTGTCTCAGTCATTGCTGTTGTATGTTCGTGCTGGAGTTTTGTTGGTGTGAAAATACACTTATTTCA
  GCCAAAACATACCATTTCTACACCTCAATCCTCCATTTGCTGTACTCTTTGCTAGTACCAAAAGTAGACT
  GATTACACTGAGGTGAGGCTACAAGGGGTGTGTAACCGTGTAACACGTGAAGGCAATGCTCACCTCTTCT
  TTACCAGAACGGTTCTTTGACCAGCACATTAACTTCTGGACTGCCGGCTCTAGTACCTTTTCAGTAAAGT
  GGTTCTCTGCCTTTTTACTATACAGCATACCACGCCACAGGGTTAGAACCAACGAAGAAAATAAAATGAG
  GGTGCCCAGCTTATAAGAATGGTGTTAGGGGGATGAGCATGCTGTTTATGAACGGAAATCATGATTTCCC
  TTGTAGAAAGTGAGGCTCAGATTAAATTTTAGAATATTTTCTAAATGTCTTTTTCACAATCATGTACTGG
  GAAGGCAATTTCATACTAAACTGATTAAATAATACATTTATAATCTACAACTGTTTGCACTTACAGCTTT
  TTTTGTAAATATAAACTATAATTTATTGTCTATTTTATATCTGTTTTGCTGTAACATTGAAGGAAAGACC
  AGACTTTTAAAAAAAAAGAGTTTATTTAGAAAGTATCATAGTGTAAACAAACAAATTGTACCACTTTGAT
  TTTCTTGGAATACAAGACTCGTGATGCAAAGCTGAAGTTGTGTGTACAAGACTCTTGACAGTTGTGCTTC
  TCTAGGAGGTTGGGTTTTTTTAAAAAAAGAATTATCTGTGAACCATACGTGAT
  
  ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCG
• Restriction Sites: SgfI-MluI
• OTI Disclaimer: Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as 10 ug dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials.

Reference Data

• RefSeq: NM_001718.4
• Summary: 'This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates a wide range of biological processes including iron homeostasis, fat and bone development, and ovulation. Differential expression of this gene may be associated with progression of breast and prostate cancer. Mutations in this gene may be associated with iron overload in human patients. [provided by RefSeq, Jul 2016]'
• Locus ID: 654