KCNA3 (NM_002232) Human 3' UTR Clone

CAT#: SC214345

3`UTR clone of potassium voltage-gated channel shaker-related subfamily member 3 (KCNA3) for miRNA target validation

Specifications

Product Data

• Vector: pMirTarget
• Species: Human
• Transfection Reporter: RFP
• Assay Reporter: Luciferase
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Symbol: KCNA3
• Synonyms: HGK5; HLK3; HPCN3; HUKIII; KV1.3; MK3; PCN3
• ACCN: NM_002232
• Insert Size: 1436
• Sequence Data:
  Insert Sequence

  >SC214345 3'UTR clone of NM_002232
  The sequence shown below is from the reference sequence of NM_002232. The complete sequence of this clone may contain minor differences, such as SNPs. Red=Cloning site Blue=Stop Codon
  
  
  CAATTGGCAGAGCTCAGAATTCAAGCGATCGC
  
  CCAACTCTTGTGTCAACATCAAAAAGATATTCACCGATGTTTAATATGTGATACAAGTGACATGCTGTGC
  TCAGTATTGTGTGGAACGTGCCCCCTTGGTCTGCCTATGCCCTTGTTTTATACATTTCCAGACCATTCAT
  CAAGGAAAGGACCTGAAGAAGTGGAAAGCACACTTCATTCTCCCTCTCCCTGCTGCTTCATACTGAAACA
  GGTGCCTGTTTTGCAAGTGGGCTGCATTCTCTCAGCTCTCCTTTTCCCTCTTACCCTCTCTCTCTTAACA
  TTGTAAACAACAGACTTACGTTAAACTTCATTTCTAGTACACGCCCTATTTAAAAAAGAGCAGTACATCC
  TGGGAGGAAATGAAACTAAAGAACAGTTAGAGTAACTGTTTAACCTCAGAATTTTAAAGGCAGTTGTTTC
  TTTCCTAAGCACATCAATTCGTAGTAAATGATGCTTCGGTTTGATGGACCTTTCAACGTTATTTATTGAA
  TATGTATTTCGGTTGCCTACCCTGTAGATATGTGGATGAAGAGTCTAACTAGAATAATGACTTGTAAACC
  CACCATGAGTTATTTGGTTTTTGACTTAAATTCCTATTTGAATCCCCTTTCCCGGAATTTTAAGTGTCTC
  TACAACTTTGAATAAAGGGAAATGCCCAAGATGTCCTGATCTGACTAATTAGTTTAATTCTTTCGGGCTT
  GCTAAGCATTTCTAAAGCATTAGACTAACAGATTCCTGTGAAGTTCTGTGCATATGTCCCAGCCCCAACA
  ACTATCAAAGTCTAGAAACAGATGTTTTCAGTGTTGCTGAGAGAAACAAAAAATTTCCTAATGCATCTGA
  GAGATAAGCTTCGGCAGTATCACAAGAAGATTAAAGTGGCAGACACCCCTTCCAGCGGAAGTTACTAATT
  CGGACCTGACTGATGCAGTTTCCATAGCAACCCATGTTTCCTGGGAAACCCGAAAAAGGTTGTCATGGCA
  TCTCTTGCTCTCTAGCCCCACCTCCCAGCCCCTGCCGTTTCCACAGTAACCTTTCCAGATGGTTCCTACT
  TAAATGATTTCATAAGGAAAACCACTGTTTGAATAAGCCGCACAAAAAATAAAGTTAAGTCTGAGACTCT
  AAGGAGGTGAAATGAATCCCAAATGCATTTTTTAACTATGAAAATCATTATGTCATTCCATAATGACTGA
  ATCAAGGAGGAAAATATGGTGTTTGGAATGTTAGATATTAACCACAATAAGGCATGATCTGGATTAAATG
  CCATTTATTAGGCAATAATTTTTAAAGATGCTTCTCTACAGTTTTCTTTCTCCAAGAACTTTCAAGCCAA
  CAAATGAAATTTAAAAGCAAATGTAAAAGTGTTCTGTACATAAGCAAATGAGAGATTCGATCAGTGTGCC
  TGAAACCTTACTACAAGGGACCTTCAGGCTTTCTCT
  
  ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCG
• Restriction Sites: SgfI-MluI
• OTI Disclaimer: Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).

Reference Data

• RefSeq: NM_002232.3
• Summary: Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed rectifier class, members of which allow nerve cells to efficiently repolarize following an action potential. It plays an essential role in T-cell proliferation and activation. This gene appears to be intronless and it is clustered together with KCNA2 and KCNA10 genes on chromosome 1. [provided by RefSeq, Jul 2008]
• Locus ID: 3738