C8orf4 (NM_020130) Human 3' UTR Clone

CAT#: SC214648

3`UTR clone of chromosome 8 open reading frame 4 (C8orf4) for miRNA target validation

Specifications

Product Data

• Vector: pMirTarget
• Species: Human
• Transfection Reporter: RFP
• Assay Reporter: Luciferase
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Symbol: C8orf4
• Synonyms: C8orf4; TC-1; TC1
• ACCN: NM_020130
• Insert Size: 1467
• Sequence Data:
  Insert Sequence

  >SC214648 3'UTR clone of NM_020130
  The sequence shown below is from the reference sequence of NM_020130. The complete sequence of this clone may contain minor differences, such as SNPs. Red=Cloning site Blue=Stop Codon
  
  
  CAATTGGCAGAGCTCAGAATTCAAGCGATCGC
  
  CAGTTTCTGAAACTGCGGAAATATTCCATCAAAGTTCACTGAAGAGAAGAGGATGGATAAGGACGTTATC
  CAAGAATGGACATTCAAAGACCAAGTGAGTTTGTGAGATTCTAACAGATGCAGCATTTTGCTGCTACCTT
  ACAAGCTTCTCTTCTGTCAGGACTCCAGAGGCTGGAAAGGGACCGGGACTGGAAAGGGACCAGGACTGAA
  CAGACTGGTTACAAAGACTCCAAACAATTTCATGCCCTGTGCTGTTACAGAGGAGAACAAAATGCTTTCA
  GCAAGGATTTGAAAACTCTTCCGTCCCTGCAGGAAAGGATTGATGCTGATAGAAGAGCCTGGACAGATGT
  AATGAGAACTAAAGAAAACAGATGGCTGGAGATGACATTTATCCAGGGTCACTTTGTCAGGCCCTAGGAC
  TTAAATCGAAGTTGAACTTTTTTTTTTTTTTTTAACCAAATAGATAGGGGAAGGGAGGAGGGAGAGGGAG
  GACAGGGAGAGAAAATACCATGCATAAATTGTTTACTGAATTTTTATATCTGAGTGTTCAAAATATTTCC
  AAGCCTGAGTATTGTCTATTGGTATAGATTTTTAGAAATCAATAATTGATTATTTATTTGCACTTATTAC
  AATGCCTGAAAAAGTGCACCACATGGATGTTAAGTAGAAATTCAAGAAAGTAAGATGTCTTCAGCAACTC
  AGTAAAACCTTACGCCACCTTTTGGTTTGTAAAAGGTTTTTTATACATTTCAAACAGGTTGCACAAAAGT
  TAAAATAATGGGGTCTTTTATAAATCCAAAGTACTGTGAAAACATTTTACATATTTTTTAAATCTTCTGA
  CTAATGCTAAAACGTAATCTAATTAAATTTCATACAGTTACTGCAGTAAGCATTAGGAAGTGAATATGAT
  ATACAAAATAGTTTATAAAGACTCTATAGTTTCTATAATTTATTTTACTGGCAAATGTCATGCAACAATA
  ATAAATTATTGTAAACTTTGTGGCTTTTGGTCTGTGATGCTTGGTCTCAAAGGAAAAAATAAGATGGTAA
  ATGTTGATATTTACAAACTTTTCTAAAGATGTGTCTCTAACAATAAAAGTTAATTTTAGAGTAGTTTTAT
  ATTAATTACCAAACTTTTTCAAAACAAATTCTTACGTCAAATATCTGGGAAGTTTCTCTGTCCCAATCTT
  AAAATATAAAATATAGATATAGAAGTTCATAGATTGACTCCTTGGCATTTCTATTTATGTATCCATTAAG
  GATGAGTTTTAAAAGGCTTTCTCTTCATACTTTTGAAAAATTTCTTCTATGATTACAGTAGCTATGTACA
  TGTGTACATCTATTTTTCCCAAGCAATATGTTTTGGGTTTAGAGTCTGAGTGATGACCAAGATTCTGTGT
  GTTACTACTGTTTGTTTAATAGGAACAAATATAGAAATAATATTATCTCTTTGCTTATTTCCCGTTA
  
  ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCG
• Restriction Sites: SgfI-MluI
• OTI Disclaimer: Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).

Reference Data

• RefSeq: NM_020130.3
• Summary: This gene encodes a small, monomeric, predominantly unstructured protein that functions as a positive regulator of the Wnt/beta-catenin signaling pathway. This protein interacts with a repressor of beta-catenin mediated transcription at nuclear speckles. It is thought to competitively block interactions of the repressor with beta-catenin, resulting in up-regulation of beta-catenin target genes. The encoded protein may also play a role in the NF-kappaB and ERK1/2 signaling pathways. Expression of this gene may play a role in the proliferation of several types of cancer including thyroid cancer, breast cancer and hematological malignancies. [provided by RefSeq, Nov 2011]
• Locus ID: 56892