DISC1 (NM_001012958) Human 3' UTR Clone

CAT#: SC214772

3`UTR clone of disrupted in schizophrenia 1 (DISC1) transcript variant Es for miRNA target validation

Specifications

Product Data

• Vector: pMirTarget
• Species: Human
• Transfection Reporter: RFP
• Assay Reporter: Luciferase
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Symbol: DISC1
• Synonyms: C1orf136; SCZD9
• ACCN: NM_001012958
• Insert Size: 1496
• Sequence Data:
  Insert Sequence

  >SC214772 3'UTR clone of NM_001012958
  The sequence shown below is from the reference sequence of NM_001012958. The complete sequence of this clone may contain minor differences, such as SNPs. Red=Cloning site Blue=Stop Codon
  
  
  CAATTGGCAGAGCTCAGAATTCAAGCGATCGC
  
  GACATCCTGAACCAAACTCCTATTAATGAAACTTCCCAAATTTAAACAAAGCAAGACAAATAGATATCCA
  CACAGCGTAGATCATGACTTCTTTAGACATCATGAAAAGAAAAAGAGGACCCACGTGGAAGAATACGCTC
  ATTTATGATCAGGGTAGCATCATATTCCTCTCCCTTTTAACATTATTTCAGGATAGCAGCTGTCTGGATG
  CTGGCCATGGGCTTGAAAAAAACCAGGTGGGCATTTCTGCCCACTGTACCGTTTCTCCCATGCGTTTCCC
  AGTCCCCTGTCATGGCATGAAAAAACCGCTATTGTTCTGTGTTGGGACAATTAGATTTTTGTAGGGGGGA
  GAAACCACCCAAAAGCAAATGGAAAAATATGCTATGATTAATGTCAGTTACGGGAATTAAACTTCGGAGG
  CCTTTAGGACAATTATGAAGGAATCATTTTCCCCTTGGTGGCAATATGTACTACAGTTGTCCCTTGATAT
  CCATGGGGGATTAATTCCAGGACGCCTGTGGATACAGAAATCCACGTGTACTCAAGTCTTGTTTTCAGTG
  GATATGAAAAGTCGGCCCTCCATATCTGCAGGTTTTACACTTGGCGAATGCTGTATTTTTGATTCATGTT
  GGATTAAGGATCTGGAACCCCTGATACAGACTGTATTTATTGAAAAAAAAGTCTGCCTATGAGTAGACTC
  ACATGTTAAAACCCGTGTTGTTCAAGGGTCAACCATAACTGCAGGCAGAACATCTGGGCAGGAAGCTCCT
  GCAGGAAGACCTGTAAACTCAGGTCTGTGGAACGGCGATGATCTTCTTCCCTTGCTTCCAGAATTATTGC
  TGTGAGATCAGGTGCACTGGCTACGACCTTACTCTTTGTGCAGAACTTATTTCTGGTCTGGTTTAAGTGA
  ACGTTATTCTTTCTGTGCAGTCCTGTGGTTACATCAAAGGTTAAATTTCATATAGCATGTCTGTTATATC
  AGACTTCTCTGATGGCCTGTCCAGAGCAAACATTTTAAAATATTGGTCCTATTCTGTCTTATAACAGTCT
  GCTCTGGTGATTTTTGTCTCATCAATTGGATTATGACACTGTCAGCCACTGTTAGTGTTATTCTCAAATT
  CAGTCTTCCATTCATCTCTCCTTCCCTTCCCTGGCAGACAGACTTCTGCAGCCACTGGGACTGTTGGGGT
  GAGGAAAGGCAAGAACCGATGTTTCATTCTCTCCCTCCCTTCTTCCTCCCTCTTTTTTGTTGGTTGTGGG
  GTGGGCTACATCTTCTTACCCAAACAACCAGGAGCATTTGTTGGCAAGTTTATTGTGCCCAGTGCCGATG
  TCTGGACAATTAATTCCCTAGGTCAGTGGCTTTCACAGTTTGTGATGGTGACTCCAGGAAGGAAACTCAC
  CATGACCCTGTATATACATAGAACAAAAATGCAGCCCACTCTGATATTGTATTTGTTCTATTCTAGTTCA
  TTAAAAGTGAATGTTGGTCTTCATCC
  
  ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCG
• Restriction Sites: SgfI-MluI
• OTI Disclaimer: Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).

Reference Data

• RefSeq: NM_001012958.1
• Summary: This gene encodes a protein with multiple coiled coil motifs which is located in the nucleus, cytoplasm and mitochondria. The protein is involved in neurite outgrowth and cortical development through its interaction with other proteins. This gene is disrupted in a t(1;11)(q42.1;q14.3) translocation which segregates with schizophrenia and related psychiatric disorders in a large Scottish family. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
• Locus ID: 27185