SOCS3 (NM_003955) Human 3' UTR Clone

CAT#: SC215826

3`UTR clone of suppressor of cytokine signaling 3 (SOCS3) for miRNA target validation

Specifications

Product Data

• Vector: pMirTarget
• Species: Human
• Transfection Reporter: RFP
• Assay Reporter: Luciferase
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Symbol: SOCS3
• Synonyms: ATOD4; CIS3; Cish3; SOCS-3; SSI-3; SSI3
• ACCN: NM_003955
• Insert Size: 1646
• Sequence Data:
  Insert Sequence

  >SC215826 3'UTR clone of NM_003955
  The sequence shown below is from the reference sequence of NM_003955. The complete sequence of this clone may contain minor differences, such as SNPs. Red=Cloning site Blue=Stop Codon
  
  
  CAATTGGCAGAGCTCAGAATTCAAGCGATCGC
  
  GGAGTTCCTGGACCAGTACGATGCCCCGCTTTAAGGGGTAAAGGGCGCAAAGGGCATGGGTCGGGAGAGG
  GGACGCAGGCCCCTCTCCTCCGTGGCACATGGCACAAGCACAAGAAGCCAACCAGGAGAGAGTCCTGTAG
  CTCTGGGGGGAAAGAGGGCGGACAGGCCCCTCCCTCTGCCCTCTCCCTGCAGAATGTGGCAGGCGGACCT
  GGAATGTGTTGGAGGGAAGGGGGAGTACCACCTGAGTCTCCAGCTTCTCCGGAGGAGCCAGCTGTCCTGG
  TGGGACGATAGCAACCACAAGTGGATTCTCCTTCAATTCCTCAGCTTCCCCTCTGCCTCCAAACAGGGGA
  CACTTCGGGAATGCTGAACTAATGAGAACTGCCAGGGAATCTTCAAACTTTCCAACGGAACTTGTTTGCT
  CTTTGATTTGGTTTAAACCTGAGCTGGTTGTGGAGCCTGGGAAAGGTGGAAGAGAGAGAGGTCCTGAGGG
  CCCCAGGGCTGCGGGCTGGCGAAGGAAATGGTCACACCCCCCGCCCACCCCAGGCGAGGATCCTGGTGAC
  ATGCTCCTCTCCCTGGCTCCGGGGAGAAGGGCTTGGGGTGACCTGAAGGGAACCATCCTGGTACCCCACA
  TCCTCTCCTCCGGGACAGTCACCGAAAACACAGGTTCCAAAGTCTACCTGGTGCCTGAGAGCCCAGGGCC
  CTTCCTCCGTTTTAAGGGGGAAGCAACATTTGGAGGGGATGGATGGGCTGGTCAGCTGGTCTCCTTTTCC
  TACTCATACTATACCTTCCTGTACCTGGGTGGATGGAGCGGGAGGATGGAGGAGACGGGACATCTTTCAC
  CTCAGGCTCCTGGTAGAGAAGACAGGGGATTCTACTCTGTGCCTCCTGACTATGTCTGGCTAAGAGATTC
  GCCTTAAATGCTCCCTGTCCCATGGAGAGGGACCCAGCATAGGAAAGCCACATACTCAGCCTGGATGGGT
  GGAGAGGCTGAGGGACTCACTGGAGGGCACCAAGCCAGCCCACAGCCAGGGAAGTGGGGAGGGGGGGCGG
  AAACCCATGCCTCCCAGCTGAGCACTGGGAATGTCAGCCCAGTAAGTATTGGCCAGTCAGGCGCCTCGTG
  GTCAGAGCAGAGCCACCAGGTCCCACTGCCCCGAGCCCTGCACAGCCCTCCCTCCTGCCTGGGTGGGGGA
  GGCTGGAGGTCATTGGAGAGGCTGGACTGCTGCCACCCCGGGTGCTCCCGCTCTGCCATAGCACTGATCA
  GTGACAATTTACAGGAATGTAGCAGCGATGGAATTACCTGGAACAGTTTTTTGTTTTTGTTTTTGTTTTT
  GTTTTTGTGGGGGGGGGCAACTAAACAAACACAAAGTATTCTGTGTCAGGTATTGGGCTGGACAGGGCAG
  TTGTGTGTTGGGGTGGTTTTTTTCTCTATTTTTTTGTTTGTTTCTTGTTTTTTAATAATGTTTACAATCT
  GCCTCAATCACTCTGTCTTTTATAAAGATTCCACCTCCAGTCCTCTCTCCTCCCCCCTACTCAGGCCCTT
  GAGGCTATTAGGAGATGCTTGAAGAACTCAACAAAATCCCAATCCAAGTCAAACTTTGCACATATTTATA
  TTTATATTCAGAAAAGAAACATTTCAGTAATTTATA
  
  ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCG
• Restriction Sites: SgfI-MluI
• OTI Disclaimer: Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).

Reference Data

• RefSeq: NM_003955.3
• Summary: This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene is induced by various cytokines, including IL6, IL10, and interferon (IFN)-gamma. The protein encoded by this gene can bind to JAK2 kinase, and inhibit the activity of JAK2 kinase. Studies of the mouse counterpart of this gene suggested the roles of this gene in the negative regulation of fetal liver hematopoiesis, and placental development. [provided by RefSeq, Jul 2008]
• Locus ID: 9021